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Bicalutamide is a non-steroidal anti-androgen used to treat advanced (metastatic) prostate cancer. It works by reducing the amount of testosterone in the body. Bicalutamide may be given in combination with other hormonal therapies such as luteinizing hormone releasing hormone (LHRH) analogues or in the surgical removal of the testicles (castration). Bicalutamide is administered orally as a tablet.

Other names for this medication:
Bicalutamide, Casodex, Bicalox, Bicalutamida, Bicusan, Bidrostat, Caluran, Calutide, Calutol, Capro, Cosudex, Imda, Lutamidal, Probic, Zolacos,

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Bicalutamide is used together with a luteinizing hormone releasing hormone (LHRH) analog (eg, goserelin or leuprolide) to treat stage D2 metastatic prostate cancer (cancer that has spread) in men. Bicalutamide belongs to the group of medicines called antiandrogens. It works by blocking the effects of testosterone (a male hormone), which helps stop the growth and spread of cancer cells.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

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Influence of selected carbohydrate drinks on cycling performance and glycogen use. They revealed homogeneity of binding sites also by kinetic experiments, thus with high probability being monoclonal. Birt-Hogg-Dube syndrome: an autosomal dominant disorder with predisposition to cancers of the kidney, fibrofolliculomas, and focal cutaneous mucinosis.

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This study shows that tendons and neurovascular structures above the ankle are at risk during small transfixion pin placement, even when using safe corridors. Therefore, informatics applications that enforce such temporal constraints are more directly useful with protocols than with guidelines. In this review we discuss novel approaches for conditional gene expression in cancer cells.

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- which lacks VxDE - by adding partially purified VxDE from spinach thylakoids. The first step in diagnosis of inappropriate shocks in patients with ICDs is to determine if the shock was delivered in response to a true tachyarrhythmia by inspecting data stored in the ICD. THE SPECTROPHOTOMETRIC DISSECTION OF THE ELECTRON TRANSFER SYSTEM OF MITOCHONDRIA ISOLATED FROM THE HEPATOPANCREAS OF CARCINUS MAENAS. This mechanism is suggested to underlie the establishment and development of human tumours, in particular of human breast cancer.

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A procedure was devised to isolate mutations that could restore conjugational competence to temperature sensitive ste mutants and simultaneously confer temperature-sensitive lethal growth phenotypes. Effect of metoprolol and d,l-sotalol on microvolt-level T-wave alternans. NOS I and its NADPH diaphorase (NADPHd) activity disappeared from the sarcolemma region shortly after denervation, and before the appearance of denervation atrophy.

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Serum follistatin is increased in PCOS patients, regardless of obesity. The algorithm indicates gross changes in the BAEP within 30 seconds and provides reliable data on latency trends. Sympathetic modulation of vagal chronotropic and arrhythmogenic influences on the heart. Although birth weight-specific neonatal and postneonatal mortality rates within cause of death categories remained stable during the 1980s, differences in the distribution of endogenous and exogenous infant deaths by cause of death suggest that the neonatal-postneonatal classification is no longer a useful proxy.

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A SENSITIVE ASSAY SYSTEM FOR DETERMINATION OF THE ICHTHYOTOXICITY OF PRYMNESIUM PARVUM. Such work gives an improved understanding of congenital lesions seen ophthalmologically in man as well as those encountered in veterinary ophthalmology. The role of transglutaminases in neurodegenerative diseases: overview.

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The possible role of viral infections in the inception of asthma has been the matter of considerable debate. The action of 1S,3R-ACPD on basal cAMP formation was not reproduced by the ionotropic receptor agonists N-methyl-D-aspartate, kainate, and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate and was antagonised by L-2-amino-3-phosphonopropionate (L-AP-3). The authors analyzed differences in size and position of treatment fields as indicated by three observers (two radiotherapists and one neuroradiologist) using CT or MR based radiotherapy planning procedures for cerebral-gliomas. Further observations are needed to better investigate the role of GSTT1 on the 1-OHP levels. Nevertheless metabolic factors such as hyper- or dyslipoproteinemia may significantly modify and accelerate the process of glomerular scarring.

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This scheme was constructed to identify family interactions that are conceptually relevant to adolescent ego development. Novel food-grade plasmid vector based on melibiose fermentation for the genetic engineering of Lactococcus lactis. Areas of further research are suggested before irradiation could be considered for practical application in some of these temperate fruits. Site-directed mutation on the only universally conserved residue Leu122 of small heat shock protein Hsp16.3.

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Expression and antigenicity of survivin, an inhibitor of apoptosis family member, in bladder cancer: implications for specific immunotherapy. per dl., which in each case is improved or stable compared to the preoperative determination. Graphite furnace atomic absorption spectroscopy was used to demonstrate a fivefold increase in the median plasma aluminium levels of four patients undergoing therapeutic plasmapheresis. Serial computed tomography (CT) scans of prostate patients were taken at 0.5 cm intervals for treatment planning purposes.

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Moreover, this study suggests that: 1) transient dyskinesias are mainly related to thalamic ischemic injury, and 2) small vessels disease is the main etiology. This type of ligand imprinting by sequestering of activated Stat may contribute to the specificity of Stat nuclear transcription. Patients with biopsy-proven squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx, or larynx were randomly assigned to one of the following treatments: prophylactic trolamine emulsion, interventional trolamine emulsion, or declared institutional preference.

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Many primary care physicians find caring for elderly patients difficult. Primary cerebral lymphoma: a study of 47 cases probed for Epstein-Barr virus genome.

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Identity-relevant events and psychological symptoms: a cautionary tale. Murine NIH3T3 cells were transfected with pCAL-MDR-IRES-ZEO constructs carrying either wild-type (WT), C3583T, or T3587G MDR1 cDNA and selected with zeocin.

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The right of access to health care for HIV patients in developing countries has been weakened by the 1999 revision of the Helsinki Declaration. Fertilization, especially applying inorganic fertilizer, significantly increased the abundance and primary productivity of phytoplankton and the biomass of zooplankton. The control rats were injected with saline solution, and the brain sections were processed similarly as described above. In addition, careful evaluation of non-microbial causes for shifts in isotopic composition is essential for a reliable interpretation.

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Nitric oxide (NO) is considered a diffusible messenger involved in neuronal communication, although the post-synaptic target cells of NO action and the associated biological function in the CNS are still a matter of controversy. Tumor reductive surgery followed by high-dose chemotherapy might be a useful approach in patients with metastatic choriocarcinoma even in cases of rare tumor sites. Optimization of irradiation conditions for photon activation analysis of biological and environmental samples using a high power electron accelerator. We propose a simple design method for an efficient surface microstructure from the viewpoint of reflected diffraction.

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Greater enrollment in HMOs, with more competitive bidding by hospitals for managed-care contracts, an important element of proposed managed-competition health care reforms, does not seem to lower hospital administrative costs. The aim of this review is to show the dentistry community the characteristics of the Cockayne s syndrome by means of a clinical case. The pH value at which the greatest fluorescence deactivation is found is close to that necessary for optimal catalytic activity and for maximal inhibition by ascorbate. The changes induced by the cold stress in the cardiovascular variables in the placebo and propranolol experiments were not statistically different.

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An original inner ear neuroepithelial degeneration in a deaf Rottweiler puppy. A surgical technique utilizing a bovine xenograft bioprosthesis has been developed for stabilizing a chronically unstable lateral ankle.

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An electrospray ionization source for integration with microfluidics. Energy and Electron Transfer Systems of Chlamydomonas reinhardi. We studied this relationship further in an attempt to better understand pathogenetic mechanisms of vasculitis.

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Exogenous free fatty acid, added to the acetylation incubations, increased the inhibition seen in the presence of MgATP. The authors report the results of a prospective study evaluating the role of serum TPA (S-TPA) in bladder carcinoma. The associations and changes of various adhesion molecules with HGF treatment were investigated by inhibition assays, Western blot analysis, and immunofluorescence staining. The effect of seatbelt use on injury patterns, disposition, and hospital charges for elders. Preoperative diagnosis of primary cancer of the gallbladder by ultrasonography and computerized tomography

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Phenotypic analysis of genetically engineered mice has provided evidence that cell adhesion molecules are critically involved in the interaction of myelin-forming glial cells with axons, the formation of regularly spaced myelin internodes along axons and the organisation of paranodes and the myelin-free gaps separating the internodes, the nodes of Ranvier. It is established that the both complexes are the inhibitors of phospholipase A2, under these conditions tocopherylquinone complex with proteins-acceptors more intensively decreases Km of the enzyme than the complex tocopherol-proteins-acceptors. The physical properties of a second functional group are expected to exert their effect(s) at three points in the metabolic activation of 2,7-disubstituted fluorene derivatives: initial reduction of the nitro group (redox effect), stabilization of the hydroxylamine (inductive effect), and stabilization/destabilization of the nitrenium ion (resonance and inductive effects).

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Angiotensin-converting enzyme inhibitors as neutralizers of hydroxyl radical Myelin basic protein induces heme oxygenase-1 in human astroglial cells. These methods were observed by comparing the functional results of tibial reconstruction patients versus foot resurfacing procedures.

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This study provides support for the belief that, in most cases, colic is self-limiting and does not result in lasting effects to maternal mental health. The authors determined the load and localization of HPV DNA in a subset of tonsillar carcinomas and their metastases. Our findings provide evidence for a naturally occurring animal model of EHEC-induced systemic disease that closely resembles human HUS.

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Utilising dais to impart health and nutrition education: impact on growth. Targeting of internalized antigen may be mediated by receptor-associated chaperones, and may be a general mechanism for optimizing the presentation of specifically bound and endocytosed antigens in b lymphocytes and other antigen-presenting cells. Textile arterial prostheses: is water permeability equivalent to porosity? In this method, latent fingerprints become visible in rich detail without the background black staining known from the application of ninhydrin solutions to thermal paper. Deletion of HSX1 does not suppress the tub2-104 mutation by misreading at the AGG codons in TUB2.

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