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Dutasteride works by blocking the conversion of the hormone testosterone to the more potent hormone dihydrotestosterone. It does this by blocking an enzyme called 5-alpha reductase. Dihydrotestosterone is partly responsible for making the prostate enlarge. Therefore, a reduced amount of dihydrotestosterone in the prostate causes it to shrink. This helps you to pass urine more easily.

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Furthermore, alpha-LA greatly suppressed in vivo bone loss induced by RANKL or TNF-alpha in a calvarial remodeling model. At operation, the tumor was found to have already invaded the surrounding tissue. Study of rat skull-brain specimens after implantation of polyester meshes. Platelet 5-HT concentration was significantly higher in veterans with psychotic PTSD than in veterans with non-psychotic PTSD, veterans without PTSD, or in control subjects.

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Three cases with C1 posterior spondyloschisis are presented with successful atlantoaxial arthrodesis using laterally placed wires to avoid the midline defect of the atlas. These mechanosensory/nociceptive cells display a number of differences from unactivated tail sensory neurons innervating other sites: slow depolarization of the soma observed immediately after training, decrease in soma action potential threshold, and enhancement of monosynaptic EPSPs to identified motor neurons. Chronic fatigue syndrome, a case of high anti-HHV-6 antibody titer and one associated with primary hyperaldosteronism Short-term survival (survival for greater than 24 hours) occurred in 111 instances (37 percent).

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The majority of primary intrahepatic stones are calcium bilirubinate stones, but intrahepatic stones with high cholesterol purity have recently been recognized. Ultrastructural localization of peroxidase in atherosclerotic lesions of pigeons. The present review discusses contribution of the extrinsic and intrinsic pathways of blood coagulation in thrombogenicity of atherosclerotic plaque and factors determining the overall procoagulant/anticoagulant balance. Age, time until resolution of glycosuria, and a rise in serum creatinine level did not have a consistent relationship with glycosuria associated with angiotensin-converting enzyme inhibitor therapy. Immunoglobulins were precipitated from large volumes of dilute blood plasma and the precipitated flocs were recovered by centrifugal separation from the liquor containing contaminating proteins, including albumin.

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Knowledge of the molecular details of the secretion pathway allows us to rationally exploit these features in heterologous protein production biotechnologies and in the development of novel antibiotics. The two major components correspond to MT-1 and MT-2, which were characterized by amino acid analysis. When frequency of intercourse was statistically controlled for, there were no significant differences between those with and those without UTI regarding the type of contraceptive method used.

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It is postulated that the neurohypophysial peptides may have a regulatory function in the secretion of catecholamines. During mesenchymal infiltration and osteogenic responses on days 3-14, moderately increased expression of BMP-2, -3, -4, -7, and BMP-R1a was found, with immunostaining observed among infiltrated mesenchymal cells and differentiated osteoblasts lining bony trabeculae. The details are presented together with a summary of different frames and modifications available for ears, nose and face abnormalities. Ultrastructural localization of human papilloma virus by nonradioactive in situ hybridization on tissue of human cervical intraepithelial neoplasia.

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The sciatic nerve action potential of the infected animals showed diminished amplitude and prolonged latency. Patients whose eyes had cataract, glaucoma, cystoid macular edema, or other complications affecting vision were excluded. It is concluded that the dormancy of Xanthium involves an inadequacy in the embryo for rupture of the testa.

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Consider that the reduction of rolling resistance, decrease in downhill turning tendancy, and required turning force would likely be even more important to the user with marginal physical capacity. The theme of the current study is to investigate the value of combining AIDS drugs and modifiers of cellular uptake into macromolecular conjugates having novel pharmacological properties.

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The expression of GLUT-1 protein was then compared to that of experimental diabetic rats to test whether the diabetic state would affect the regulation of the glucose transporter during the early postimplantation periods (9.5-14.5 days), as we have previously demonstrated that GLUT-1 protein in embryo and VYS was down-regulated in culture with hyperglycemic medium. A material decoy of biological media based on chitosan physical hydrogels: application to cartilage tissue engineering. Further examination in vivo over 8 weeks revealed that subcutaneous implantation of hydrated matrix degraded in vivo three times faster than in vitro. In all patients, alterations of ossification were found to a varying degree, including calcification of the anterior spinal ligament, vertebral hyperostoses at the anterosuperior and anteroinferior margins of the vertebral bodies, unilateral bridging of vertebral bodies, hyperostoses of the calcanei at the insertion of the plantar ligament and bone accretion at the anterolateral lips of the acetabula.

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This is the first example of a repetitive sequence in a parasite protein which is present only in the insect vector, and which therefore cannot be implicated in the mammalian host immune response. Design, synthesis, and testing of potential antisickling agents. Rats were subjected to standard conditions of hemorrhagic shock. Predictors of progression to dementia in individuals with mild cognitive impairment (MCI) define different groups with higher risks of progression. Using three independent cytochemical methods that characterize the DNA accessibility for acridine orange and 3H-actinomycin D and the presence in histones of free amino groups, it has been established that lymphocyte chromatin from women during threatened abortion is repressed to a greater degree than in those with normal pregnancy.

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On the influence of mechanical and physiological rest in the treatment of accidents and surgical diseases, and the diagnostic value of pain. The patient died one year after the first complex partial seizures. The presence of hydrophobins in conidiating and mycelial cultures was also examined, and it was shown that these proteins were abundant in conidiating cultures but not in mycelial cultures. The clinical potential of this approach for detecting protein disorders is discussed.

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After G-CSF therapy a significant increase in IFN-alpha production ability was detected. Over a dozen different types of DNA damage are now known to be bypassed with various degrees of efficiency and miscoding abilities by the transcriptional elongation machinery. Our study was designed to assess the importance of p53 aberrations in HCCs from Europe, where the major risk factors in hepatocarcinogenesis, aflatoxin exposure and chronic hepatitis B virus (HBV) infection, do not play a dominant role. In the case of bacterially expressed p24gag, it is shown that all of the linear, sequential epitopes presented by viral p24 during infection are retained. Subjects either produced no sputum or (acid fast) smear negative sputum.

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The adverse effects on childhood growth of poor environmental conditions are well known, and it is argued that the variation in body size found between the populations in this study were the results of marked differences in the quality of their living conditions. Common reasons for nonconfirmation were the need for further testing, medication preferable to an operation and symptoms not severe enough to warrant an operation. Studies in both animal and human subjects have shown that nicotine can function as reinforcer, albeit under a more limited range of conditions than with some other drugs of abuse. Vesicular site of action of lithium ion in choline-calcium stimulated adrenergic nerve endings of rat heart. Ultrastructural analysis of asteroid bodies: evidence for membrane lipid bilayer nature of components.

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Thus far there is little information on p53 mutations in cancers of factory workers with a history of carcinogen exposure in the workplace. Long-term ERT can enhance cholinergic function in postmenopausal women and this may be related to duration of estrogen treatment. The purpose of this study was to obtain a kinetic model of ouabain tissue distribution. Comparisons of the average duration of multiple sclerosis derived from a prevalence survey of cases alive in 1970 in a low-risk area (Los Angeles County, California) and a high-risk area (King and Pierce Counties, Washington) suggest that patients in the high-risk area had a longer duration of disease than patients in the low-risk area.

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Many anticancer drugs are classified as either weak bases or molecules whose binding to cellular structures is pH dependent. This paper describes a research study on empathy in physicians of different specializations. Mild intestinal manipulation or lipopolysaccharide initiates an intense inflammatory response within the intestinal muscularis, resulting in paralytic ileus.

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The femoral hemodynamics are much more disturbed than the cerebral ones in vascular deconditioning. EXProt: a database for proteins with an experimentally verified function. Our data point out a quite different behaviour of Estradiol and Progesterone cytoplasmic Receptors in the endometrium of women with mastodynia and controls. Hemostasis was achieved with a harmonic scalpel, a microwave tissue coagulator, an argon beam coagulator and autologous fibrin glue. In normal ephitelial cells, at adherens junction level, beta-catenin links cadherins to the actin cytoskeleton.

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In the present experiment, three rhesus monkeys were allowed to choose between saline and several doses of d,l-cathinone or cocaine as well as between several doses of both drugs in a discrete-trial choice procedure. Laparoscopy can be used for staging in patients with advanced cervical cancer who are scheduled for definitive radiotherapy. Conformational properties of four peptides corresponding to alpha-helical regions of Rhodospirillum cytochrome c2 and bovine calcium binding protein. Of five patients who remained in long-term remission (mean 144 months), three did not have detectable MRD at the end of induction therapy (2 months) and all five were MRD-negative at the end of treatment (36 months). In contrast, the majority (15 of 23) of down-regulated genes were of unknown or poorly characterized functions.

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The disinfection of flexible fibre-optic nasendoscopes out-of-hours: confidential telephone survey of ENT units in England. The decreased rate of ovulation in the older birds and the increase with age in the size of the follicles ovulated is thought to be associated with a reduced rate of recruitment of follicles for rapid growth followed by a prolonged period of follicular growth and development. Internal spermatic vein diameter and age at operation reflect the response to varicocelectomy. All were diffusely present in three of three malignant tumors, except vesicular nuclei and spindle cell morphology, which were present diffusely in two tumors and focally in one tumor.

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Granulocyte migration in vivo and in vitro in healthy children of parents with aspirin-sensitive asthma. Experiments on dye-leakage activity and membrane translocation of peptides suggest that dimers and monomers form pores through lipid membranes, although the pore formation may be accompanied by membrane disturbance. Dose response of topical carbamylcholine chloride (carbachol) in normotensive and early glaucomatous beagles. Participants represented the views of district general and teaching hospital dermatologists, a fundholding general practitioner, a health commissioning agent and patient support groups.

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A new autoperfusion technique for aortic reconstruction of suprarenal aortic aneurysm. Alterations in the distribution of fibronectin and laminin in the diabetic human eye. HISTOLOGICAL STUDIES ON THE REINNERVATION OF DENERVATED MUSCLE WITH SPECIAL REFERENCE TO THE COLLATERAL BRANCHING Patients with chronic granulomatous disease showed no CL, and one of their mothers (1/3) showed low CL, suggesting she is a carrier.

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Within 4 h of institution of the hyperinsulinaemic clamp significant reductions in serum levels of potassium, phosphorus, cholesterol, total protein and albumin were noted. Neurotensin immunoreactive (NT-IR) neuronal perikarya are present in small numbers in the bed nucleus of the stria terminalis, lateral olfactory stria, substantia innominata, caudate nucleus and putamen of the human infant forebrain. We describe a case of anomalous origin of the left coronary artery.

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Finally, a multitaper spectrum estimator is proposed, simulated, and compared with untapered estimates. Exposure of human erythrocytes to hypoxanthine and xanthine oxidase in Krebs solution prevented an otherwise occurring hemolysis. Assessment of within-group variation in CYP1A mRNA inducibility in environmentally exposed and chemically treated Atlantic tomcod.

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An inexpensive rotary valve is used to inject the serum sample (4 microliters) into a flowing non-segmented stream of reagent which carries the sample slug through a long narrow-bore coil--where it gradually disperses--and into the nebuliser of an atomic absorption spectrometer. Purification and properties of a mammary-uterine-pituitary tumor cell growth factor from pregnant sheep uterus. However, the sudden increase in glucose concentration induced by stressing influences in intact or partially deafferented animals dropped or became totally suppressed in the preparations with isolated protocerebrum.

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The demands on NOP resources will likely be changed dramatically both in terms of quantity and quality. ORF2, which is disrupted by the IS1031A insertion in Cel1, potentially encodes the complementing function. Ultraviolet hypersensitivity of Cockayne syndrome lymphoblastoid lines--the effects of exogenous beta-nicotinamide adenine dinucleotide. The results of this study suggest that CL284,846 is a safe, rapid acting and effective sedative with some clear advantages over lorazepam with respect to unwanted cognitive and psychomotor impairments.

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Either aspirin or cardiotonic pills could significantly reverse the platelet hypersensitivity and hyperfunction. We retrospectively compared surgical results after hemiarch as compared with transverse aortic arch replacement in patients with an arch tear in acute type A dissection.

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Adverse events were common in the first two days of therapy but were well tolerated. Investigations of the pathogenesis of acquired pendular nystagmus. Lymphocyte subpopulations in normal and preeclampsia pregnancies. Detection of serum antibody response to Bacteroides bivius by enzyme-linked immunosorbent assay in women with intraamniotic infection.

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Fc receptor-mediated immune clearance correlated remarkably well with (a) a decrease of antigen specific IgG after immunization with a primary test antigen (alpha-Helix pomatia haemocyanin) (P less than 0.01) and (b) the spontaneous IgG release in vitro of B cells obtained from peripheral blood (P less than 0.01). Metabolic activation of N-OH-AAF by either the membrane-bound deacylase or the cytosolic N,O-acyltransferase caused genotoxicity via a deacetylation process. The multiple choice, viva voce and consultant marks from 327 students in the Orthopaedic Undergraduate Course at the University of Bristol were compared. Multiple regression analysis indicated positive relations between Mastery goals and the Motive to Achieve Success and Cognitive Competence.

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A-57-year-old woman had suffered from high fever, general malaise, and loss of weight (6 kg) since January, 2000. A combined score test for association and linkage analysis is introduced, based on a biologically plausible model with association between markers and causal genes and penetrance between phenotypes and the causal gene.

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Soluble factors with inhibitory, attractive and inductive roles in migration have been described, as well as molecules mediating cell-to-cell and cell-substrate interactions. The presence of abnormally shaped adrenal glands in patients with left renal agenesis and ectopy is a new diagnostic radiologic sign for these conditions.

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Basic rheology of mammalian blood: factors promoting and factors interfering with fluidity of blood. This relationship is based on the hypothesis postulating that a higher serum glucose and insulin response induced by high-glycaemic carbohydrates promotes lower fat oxidation and higher fat storage in comparison with low-glycaemic carbohydrates. However, this greater radiosensitization in intestine and kidney did not translate into bigger differences in SF2 (surviving fraction at 2 Gy) or SF3.5. Future studies may elucidate whether determination of skeletal remodelling using biochemistry adds significantly to risk determination.

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Ultrasound examination at 9 weeks of gestation in a 34-year-old primigravida showed a twin pregnancy, with discrepancy in the sizes of the two gestational sacs, whereas the crown-rump lengths and fetal heart rates were virtually identical-the result being an abnormal sac size/crown-rump length ratio (early oligohydramnios). In contrast, the detrimental effect of adiposity as measured by body mass index appeared to decline after age 65 for both measures of risk. To evaluate the incidence of congenital malformations among offspring of mothers who conceived with clomiphene citrate (CC) or with letrozole treatment for infertility.

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STUDIES ON THE EPIPHRENIC TRANSPOSITION OF THE SPLEEN IN THE TREATMENT OF PORTAL HYPERTENSION The hypothalamus is known to be intimately involved in the control of autonomic function. Cutaneous manifestations of mycobacterial infection in patients with AIDS. In this paper, we critically examine the literature to determine the weight of evidence for the application of water column partition half-times as a surrogate for the persistence criterion in the aquatic hazard identification of metals and metal compounds.

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As is the case for the assembly of protein components of the membranes in animal mitochondria, the bilayer phospholipids arise from a complicated interplay of intra- and extra-mitochondrial reactions. Dinucleotide repeat polymorphism (D10S608) adjacent to the GLUD1 locus. We have investigated the effect(s) of transforming growth factor (TGF)-beta 1 and interleukin (IL)-6 on the expression of fibrinogen and blood coagulation factors VII, IX, X mRNAs in a hepatoma cell line (Hep 3B).

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88 consecutive patients operated on for AVM located supratentorially in the years 1983-2000 were included in a retrospective analysis. Stereochemistry of aromatization of 3-hydroxy-3,5,7-androstatrien-17-one by horse placenta. The suminat tablet for kids present quantitative review suggests the existence of moderately strong associations between baseline levels of each of apoAI, apoB, and apoB/A and risk of CHD. Comparison of the antagonistic effects of different angiotensin II receptor blockers in human coronary arteries. Only the (R)-isomer, levalbuterol (LEV), is therapeutically active.

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AN ASSESSMENT OF THE ROLE OF ALPHA AND BETA CHYLOMICRA IN HYPERLIPEMIC STATES. Carbohydrate supplementation in prolonged aerobic exercise has been shown to be effective in improving performance and deferring fatigue. Insertion into the Mycobacterium smegmatis genome of the aph gene through lysogenization with the temperate mycobacteriophage Ms6. The ability of these three unlignified cell-wall preparations to adsorb the hydrophobic environmental mutagen 1,8-dinitropyrene senna medication card for amiodarone was studied.

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Studies were undertaken to characterize the transport of this antifolate in this tumor. Using laser microprobe mass analysis, we studied the ultrastructural localization of aluminum in liver and bone tissue of chronic-hemodialysis patients with proven aluminum-induced osteomalacia. Aberrations of the p14(ARF) fulcin syrup recipes and p16(INK4a) genes in renal cell carcinomas. Ivermectin-induced cell-dependent lethal effects on litomosoides carinii microfilariae in vitro.

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