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Effect of Tibolone on turnover of cholesterol to bile acids in ovariectomized rats. A study of the effect of Tibolone on the vagina in postmenopausal women. The properties of Tibolone, a synthetic steroid will be outlined and its mechanism reviewed. Effects of Tibolone and its metabolites on prolactin and insulin-like growth factor binding protein-1 expression in human endometrial stromal cells.

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This origin consists of four separate functional elements, one of which is essential. When macrophages were costimulated with various concentrations of human recombinant interleukin 1 alpha (IL-1 alpha), along with either maximum-stimulating amounts of IFN-beta or suboptimal amounts of IFN-gamma, IDO activity was upregulated in a manner similar to results obtained using the microbial products as stimuli. Diagnostic value of endothelial microscopy in surgery of the anterior segment

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The aim was to identify and study the main factors governing the transfer of carotenoids from emulsion lipid droplets to mixed micelles, presumed to be a key step in carotenoid absorption. Solid collagen gels containing human pancreatic carcinoma NOR-P1 cells and fibroblasts or minced human pancreatic carcinoma tissue were cultured under a simulated microgravity condition or a static Ig condition for seven days. During differentiation induced by serum withdrawal, induction of myogenin expression preceded that of IGF-II, the principal IGF peptide expressed by these cells.

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However, a primary pathogenetic role in alcoholic hepatitis has not been proven for this thyroid hormone mimicry. A 97-year-old woman was provoked a convulsion after taking a new quinolone antibiotic drug Levofloxacin and a non-steroidal anti-inflammatory drug Loxoprofen. The purpose of the study conducted was to clarify the question of chronic, systemic toxicity from PUVA therapy.

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Cisplatin and platinum pharmacokinetics during hyperthermic isolated limb perfusion for human tumours of the extremities. An histidine-rich peptide which permeabilizes biological membrane at pH 6.4, favored the transfection mediated by lactosylated polylysine/pDNA complexes. However, as we also show, Trx does not alter the expression of endothelial cell adhesion molecules (intercellular adhesion molecule-1, vascular cell adhesion molecule-1, CD62P, and CD62E) within 3 h.

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To examine the effects of insulin on human beta-adrenoceptor responsiveness, adenylyl cyclase activity, cyclic AMP-dependent protein kinase activity and beta-adrenoceptor radioligand binding assays were performed on permeabilized mononuclear leukocytes. Acute mountain sickness (AMS) is usually a benign and self-limited illness that befalls previously healthy individuals who ascend rapidly to high altitude without sufficient acclimatization.

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This report describes this unique laboratory animal, genetic selection programs, and its utilization in biomedical research. This study provides a data base that can be used to qualitatively and quantitatively examine the relationship between external dose and O4-EtdT over a DEN dose range covering several orders of magnitude. The degree of inhibition by hydroxymalonate of partly purified NAD(P)-linked malic enzyme activity was identical to that of both malate dependent pyruvate and progesterone formation by intact mitochondria.

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Renographic studies under standardised conditions of maximal diuresis provoked by infusion of hypotonic saline and frusemide were made on 51 patients with 54 dilated upper urinary tract systems in order to distinguish obstructed from non-obstructed systems. A therapeutic effect of (131)I on hepatoma cells in vitro and in vivo has been demonstrated after tumor-specific iodide uptake induced by mAlb-directed hNIS gene expression. The authors conclude that heparinase-I effectively restored the ACT after cardiopulmonary bypass.

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In the drowsiness, the EEG was high voltage, low frequency activity pattern. The expression pattern of NFATx, together with its functional activity, strongly suggests that NFATx plays a role in the regulation of gene expression in T cells and immature thymocytes. Polyamines, in particular spermine and spermidine (sp/spd) are the major cations found within prostatic secretions, yet their secretory mechanism in normal and neoplastic tissues has not been investigated.

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However, to consider both, the surgical and the endoscopic treatment, complementing each other, seems to be important to guarantee optimal palliation for the individual patient. There is enhanced incorporation of leucine-C(14) into proteins in cell-free preparations from livers of young rats force-fed a threonine-devoid diet for 3 days. This finding was observed for males and females and was consistent with the lower serum lT4 value observed for animals housed on room side B.

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The vowel stimuli represented tokens of Spanish /i/, /e/, and /a/ and English /i/, /I/, /eI/, /epsilon/, /ae/, /lambda/, and /a/. Both grafts were compared to the left internal mammarian artery anastomosed to the LAD.

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Membranes of Sulfolobus acidocaldarius, a thermoacidophilic archaebacterium, show novel enzymatic activities to hydrolyze PPi, ATP, and ADP at an optimal pH of 3, equal to the growth optimum. Treatment of preparations with protamines prevented the identification of the endogenous nicks.

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In general, wood is said to dull knives less than plastic, and plastic is seen as less porous than wood. Of the cat tissues studied, only extracts of pelt and female brain contained amounts of cat allergen 1 in excess of 0.50 U/ml. The frequencies of gestational age less than 38 weeks, lecithin/sphingomyelin (L/S) ratio less than 2.0, negative phosphatidylglycerol, and neonatal hyaline membrane disease were found to decrease as placental grade advanced from 0 to III. The objective of our prospective study was to determine by segregation analyses a plausible mode of inheritance within a Labrador Retriever population. Pancreatic duct obstruction, even in the absence of biliary obstruction and/or bile reflux into the pancreatic duct, can trigger acute hemorrhagic necrotizing pancreatitis.

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Sequence analysis of a 40.2 kb DNA fragment located near the left telomere of yeast chromosome X. SCALENE NODE BIOPSY IN LOCALLY ADVANCED PRIMARY BREAST CANCER OF QUESTIONABLE OPERABILITY.

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Major complications were relatively common in early operations, but with more experience morbidity has been reduced. The folding of the polypeptide chain has been established and consists of two structural domains. Independent effects of interleukin 1 on proteoglycan synthesis and proteoglycan breakdown of bovine articular cartilage in vitro. Importance and long-term utility of a multiparameter programmable pulse generator.

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The slowly perfused stump of a distal carotid artery is supposed to be a potential source of emboli into the retinal or intracranial territories. MalR was found to be homologous to the LacI-GalR family of transcriptional regulators, and MalA showed high similarity to yeast alpha-1,4-glucosidases and bacterial alpha-1,6-glucosidases. The diagnosis depends on demonstrating poor uroflow, a detrusor contraction of adequate magnitude and duration, and radiographic evidence of obstruction at the vesical neck.

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The time-dependent increase in acid secretion is also correlated with time-dependent inhibition of the peroxidase activity. PDQ uses a computer mainframe, which allows a large amount of data to be stored and made available to physicians rapidly and accurately. The biochemical basis for this form of cerebellar abiotrophy is unknown, but the lack of disease in other siblings supports an autosomal recessive mode of inheritance. In a concurrent trypanosome infection such increasing antibody levels would not be observed, leading to inaccurate diagnosis.

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Risk period for intraventricular hemorrhage of the preterm neonate is independent of gestational age. Reperfusion of isolated perfused rat hearts with 10(-9) mol/L endothelin (ET) significantly exacerbated the ischemia/reperfusion injury(I/R), in contrast, reperfusion with specific ET-antiserum dramatically alleviated myocardial I/R injury. The hemolytic product encoded by the cloned DNA fragment possessed all the properties of hemolysin II known to date: it was not inhibited by cholesterol, exhibited the Arrhenius effect, and had a relatively long (in comparison with cereolysin) lag period in erythrocyte lysis. Outcome of acute myocardial infarction in patients with prior coronary artery bypass grafting treated with combination reduced fibrinolytic therapy and abciximab.

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Cross generation lead ingestion: behavioral and physiological effects in mice. In addition the time taken to position the patient in the treatment room was also marginally shortened. Brazilian purpuric fever (BPF) is a newly described pediatric syndrome that results in significant morbidity and mortality. Twenty out of 36 patients who had been treated with a carbon fiber syndesmoplasty were followed up 12-19 months after surgery. Clinical and pathological remission of some autoimmune diseases is often obtained by corticosteroids.

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In addition, we describe how to use multiplexing for accurate and rapid typing. Abnormalities affecting the anterior part of the vertebral ring apophysis occurred exclusively in athletes and they were most common in wrestlers and female gymnasts. Preliminary comparison of the rupture of human and rabbit anterior cruciate ligaments. The profession of clinical laboratory technologist has undergone profound changes in the last decades and scientific as well as technological advancement will cause further continued evolution.

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In addition to CREB, other key TFs identified are ecotropic viral integration site-1 and SP1. The patient also suffered from urinary tract infection and was treated with oral norfloxacin. Using chi 2 analysis, survival rates were examined for patients treated with excision alone, irradiation alone, and both excision and irradiation. The analysis follows from basic geometric and sensitivity constraints found in low-profile imaging sensors. Polypeptide growth factors are probable mediators of cardiogenesis during embryonic development.

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Parameters studied were mode of detection, tumor size, axillary lymph node involvement, and histopathology. Screening patients for MRSA and VRE can be restricted against those in/from the high risk areas.

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Deeply invasive EC was associated with a consistent lack of CD44v6 expression. These data are consistent with the hypothesis that ricin A chain can exploit the ER-associated protein degradation pathway to reach the cytosol.

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Chief among these are the hepatitis viruses, particularly HBVand HCV, both of which are significantly more widespread than HIV Circumstantial evidence suggests that hemodialysis, per se, is an important risk factor for infection with HCV. Two experiments demonstrate recursive retrospective revaluation with contingency information presented in list format as well as with trial-by-trial acquisition.

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This result contradicts and, therefore, challenges the assumption in immune network models that the activation function is identical for all ligands. Effectiveness of low-energy laser treatment of patients with recurrent chronic gastrointestinal erosions

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Is cytomegalovirus infection going to be a problem among heart transplant recipients in Singapore? Changes in in vitro platelet quality parameters during platelet storage are associated with a decrease of in vivo platelet viability after platelet transfusion. Activation of lipid peroxidation in the rat brain in vivo under dichlorvos and deltametrin intoxication was established. The single-nucleotide polymorphism was typed by direct sequencing of PCR products. This latency difference decreases at shorter paired-click intervals and is attributed to adaptation of click 1 by click 2 of the previous pair.

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High 1,5-anti stereoinduction in boron-mediated aldol reactions of methyl ketones. Both pCA and FpCA enhanced dopamine and noradrenaline levels compared to saline controls. This review will focus on the biological importance of integrin and growth factor receptor crosstalk that occurs during cell growth, migration, and invasion as well as in endothelial cells during angiogenesis. Females responded faster to high call rates, and female vocal activity was greater in response to low-frequency male calls. The sensitivity of PET is highest for the evaluation of new malignancy in patients without a known primary carcinoma.

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In the last decade, numerous groups have attempted the detection of occult tumor cells in renal, prostatic, and urothelial carcinomas using the highly sensitive reverse-transcriptase polymerase chain reaction (RT-PCR). Family income and serum protein were the only important influencing factors (negative). Selective impairment of baroreflex-mediated vasoconstrictor responses in patients with ventricular dysfunction.

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By contrast, neither group had inhibited ACTH responses to stress applied during the diurnal peak (PM). In contrast, pressure overload-induced cardiac hypertrophy completely abolished this diurnal variation of metabolic gene expression. All subjects attended for review every 2 weeks during the weight loss period. Extended subtotal petrosectomy as a treatment for persistent cerebrospinal fluid (CSF) otorhinorrhoea is presented.

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In patient with early asthmatic reaction decrease of luminescence was observed during first hour only. From the earliest stage investigated (11 days post coitum) onwards, expression of CX 43 is always associated with desmin-positive cells, that is, with the myocytes. These levels of O2- release were similar in magnitude to those of macrophages from rats treated in vivo with IFN-gamma. Secondary structural effects explain increased resistance to oxyiminocephalosporins. A missense mutation within the mycobacterial inhA gene was shown to confer resistance to both INH and ethionamide (ETH) in M.

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Significance of allogenic blood transfusion on decreased survival in patients with esophageal carcinoma. Determination of principal reynolds stresses in pulsatile flows after elliptical filtering of terazosin 5 mg presentaciones discrete velocity measurements.

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T cell receptor gene rearrangements in cells with natural killer activity in the mouse. Prosthetic replacement for chronic unreduced dislocations nexx x30v review of the shoulder. IL-15 is a T(H)1-related cytokine that shares many biologic activities with IL-2. Healing of experimental ligament rupture: findings by scanning electron microscopy.

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Regulation of mammalian ribonucleotide reductase by the tumor promoters and protein phosphatase inhibitors okadaic acid and calyculin A. Effects of glucocorticoids on contractions and electric activity of lymphatic vessels In patients with suspected infarction and without contraindications, early treatment with an intravenous dose is of paramount importance. The segmental dorsal ramus neuropathy as a common cause of chronic and recurrent low back divalproex extended release tablet pain. Naltrexone may be a useful agent for induction of ovulation in women suffering from hypothalamic amenorrhea.

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The usefulness of fluoroquinolones for the treatment of mixed aerobic and anaerobic infections has been investigated since these agents started being used in clinical practice. Preclinical studies with radiolabeled monoclonal antibodies for treatment of patients with B-cell malignancies. Dipeptidyl peptidase IV (DPP4/CD26) and seprase/fibroblast activation protein alpha are homologous type II transmembrane, homodimeric glycoproteins that cardioplus capsules exhibit unique prolyl peptidase activities.

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Consequently, the data suggest that estrogens may stimulate mitogenesis of the N-nitrosomethylurea-induced mammary tumor through the polyamine pathway. This pilot study was designed to determine whether 12 professionals, four from each of three health disciplines concerned with child-abuse detection (nursing, medicine and social work), could agree on parenting risk status of 15 pregnant women. Body weight and feed intake were omeprazol iv infarmed dose-dependently decreased prior to killing of the animals.