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Carbose (Acarbose)

An antihyperglycaemic effect was observed only in the group of diabetic mice fed with 100 mg Carbose. Structural analysis of the NtMGAM-Carbose complex reveals that Carbose is bound to the NtMGAM active site primarily through side-chain interactions with its acarvosine unit, and almost no interactions are made with its glycone rings.

Other names for this medication:
Acarbose, Precose, Acarbosa, Byetta, Carbose, Diabose, Glucobay, Gluconase, Prandase,

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Carbose is used to treat type 2 diabetes. Normally, your pancreas releases insulin into the blood stream after you eat. Insulin is used by all the cells in your body to help turn the food you eat into energy. This is done by using glucose (sugar) in the blood as quick energy. When you have type 2 diabetes, insulin is still produced by your pancreas, but the amount of insulin produced may not be enough or your body may not be using it properly and you may still need more. Because of this, the insulin is not able to lower your blood sugar properly and you will have too much sugar in your blood. Carbose lowers your blood sugar by preventing the breakdown of starch into sugar. It may be used alone or in combination with another type of oral diabetes medicine called a sulfonylurea.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet

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Differential regulation of pulmonary endothelial monolayer integrity by varying degrees of cyclic stretch. In aggregate, the findings demonstrate that the local cytokine environment is critical to the induction of protective immunity following chlamydial vaccination and that GM-CSF may be a useful adjuvant for a chlamydial vaccine. Iron deficiency can lead not only to anemia but to decreased work capacity, abnormal neurotransmitter function, and altered immunologic and inflammatory defenses. Prevalence of diabetes mellitus treated with insulin and oral hypoglycemic agents in Denmark. These results are discussed in light of interactions between immune and visceral responses, and their regulation by endogenous opioids, during RS.

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Several investigators have shown that in extreme cases this can result in an accumulation of oxidatively damaged proteins as useless cellular debris. In future studies to unravel the complex mechanisms of the PNP antigens, the immunoblot technique may be a useful tool. Subsequent uptake and utilization of supplemental CoQ10 by the yeast could diminish availability for the human subject. Both the alcohol-induced reduction in the GABA(A)alpha5 subunit during development and up-regulation in adult brain may be related to learning deficits resulting in decreased learning potential caused by the developmental defect and an increased inhibition of learning resulting from increased expression as an adult.

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A case of atresia ani with rectovestibular fistulae in an alpaca (L. Differentiating autism from other handicapping conditions, especially mental retardation, has been a constant problem for public schools. Influence of a Fusarium culmorum inoculation of wheat on the progression of mycotoxin accumulation, ingredient concentrations and ruminal in sacco dry matter degradation of wheat residues.

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Ultrastructural integrity was related to myocardial tissue calcium content, with a significant negative correlation. Polymerase chain reaction for producing biotinylated human papillomavirus DNA probes for in situ hybridization. A phylogenetic analysis based on 16S rDNA sequences indicated that the new isolate is a member of the beta subclass of the Proteobacteria and represents a distinct line of descent within the family Comamonadaceae. The interdomain bridges formed by the internal aldimine with the wild type beta 2 subunit and by the external aldimine with L-serine in the K87T beta 2 subunit may further stabilize interaction with the alpha subunit because the alpha/beta interaction site contains residues from both N- and C-domains of the beta 2 subunit.

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Giant-cell tumor-like proliferation associated with a papillary transitional cell carcinoma of the renal pelvis. A 13-year-old South African Indian boy who presented with oral mucosal lesions and skin blisters due to juvenile pemphigus vulgaris is described. The embedding is carried out by using an iterative pairwise refinement strategy that attempts to preserve local geometry while maintaining a minimum separation between distant objects.

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Long-term survival after surgical treatment of aneurysms of the infra-renal aorta Expression of zTlxA, a Hox11-like gene, in early differentiating embryonic neurons and cranial sensory ganglia of the zebrafish embryo. Differentiation between hilar adenopathy and prominent pulmonary vessels is also sometimes difficult. Proteins binding to the leader of the 6.0 kb mRNA of human insulin-like growth factor 2 influence translation.

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A RecA-deficient stain of Streptococcus mutans, isolated previously, was found to be more susceptible than the prototroph organism to acid killing and also showed reduced colony-forming ability on sucrose-containing medium. Mercury secretion into bile was independent of the changes in bile flow produced by dehydrocholate (DHC) or hypertonic sucrose, but it was closely related to the rate of GSH secretion. Topical FK 506 was found to be efficient and safe for treatment of atopic dermatitis in dermatologic studies.

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Only an immediate surgical intervention up to amputation of the affected extremity can stop the fatal course. Microbial metabolism of homocyclic and heterocyclic aromatic compounds under anaerobic conditions. There was an increase in the proportion of macrophage/monocytes vs lymphocytes in the ocular lesions of treated animals.

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This review will focus on experimental data supporting this new representation of this set of autoantibodies directed against DNA, histone and the nucleosome, and their possible intervention in SLE pathogenesis. As a determinant of intercellular conductance, gap-junctional coupling is considered to influence myocardial conduction velocity.

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Two basal cell carcinomas, a nodular and a fibrosing type, and a trichoepithelioma were included as controls. The standard error of measurement was also used to quantify reliability, with the volar/dorsal alignment technique consistently producing less error than the ulnar and radial alignment techniques. A Coulter Counter was used to follow the crystallization and decrease in soluble (14) C-oxalate was measured to determine the deposition of CaOx. The auxotrophy of parasitic protozoa for purines makes purine acquisition from the host a nutritional necessity for the survival and growth of these pathogens.

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Plasma leptin levels were also markedly increased possibly explaining the observed reduction in gene expression for hypothalamic NPY. These improvements yielded a net increase of 50-fold in the packaging efficiency of the AAVp5neo and AAVp5lacZ recombinant vectors. The QSPR results show that standard heat of formation (DeltaHf), total energy (TE), and molecular weight (Mw) have dominant effect on t1/2 values of PCBs in n-hexane. Remarkably, this includes structures absent in Xenopus, such as the hair follicle and mammary gland, suggesting that conserved regulatory elements can be used to control the formation of structures peculiar to individual species. Thus, doctors involved in front-line trauma care, whether in the centre-city teaching hospital or in the rural community setting, must be properly prepared.

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Patients should have a full dental examination at the time of diagnosis of the plasma cell dyscrasia especially if bisphosphonates are to be considered as part of the therapy. Cloned fusion proteins encoding each isotype were used first to tolerogenize animals against shared epitopes, and then as immunogens to elicit a specific response. Mac bound to CD16 (FcgammaRIIIB) on the surface of human polymorphonuclear leukocytes and inhibited opsonophagocytosis and production of reactive oxygen species, which resulted in significantly decreased pathogen killing. Our results indicate that the amyloidogenic fragment of gelsolin can adopt two distinct forms, of which only one can form amyloid fibrils in vitro.

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Epidemiological investigation of human papillomavirus infection in men attending a sexually transmitted disease clinic in Hangzhou area The use of field effect transistors (FETs) in biomedical research has been in rapid progression in recent years. The incidence of both gross fetal body movements and fetal breathing movements increased, especially in the first hour after naloxone administration. Candida albicans is the single, most frequently isolated human fungal pathogen.

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Carmofur (1-hexylcarbamyl-5-fluorouracil), a derivative of 5-fluorouracil (5-FU), has been widely used in Japan as a postoperative adjuvant chemotherapy agent for colorectal and breast cancer. Our results indicate that without increasing the amounts of DNA, increased liposome concentrations within certain limits enhanced transfection efficiency.

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The plethora of surgical techniques for the reduction of inferior turbinate volume is a good indicator of unresolved controversies regarding the ideal technique. Sixty-five samples of liver tissue showing normal liver, different degrees of chronic inflammation, cirrhosis and histological features of hepatocellular adenoma and carcinoma (HCC) were included in the study.

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A transglucosidase necessary for starch degradation and maltose metabolism in leaves at night acts on cytosolic heteroglycans (SHG). This article presents some limited results from the Medical Library Association (MLA) Benchmarking Network survey conducted in 2002. There is international recognition that not only is cancer in young people on the rise but also that improvements in outcomes of cancer in young people lag well behind the advances that have been achieved for both children and older adults in the past 30 years. AM treatment resulted in a complete inhibition of the Ang II-induced increase in ANP and BNP gene expression and secretion.

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The Wittmaack temporal bone collection and possibilities for cataloguing with electronic data processing The authors conclude that the use of the Mitek Anchor System affords the surgeon a simple and effective method for the repair of acute, distal, tendo Achillis rupture when other methods cannot be used because of the location of the rupture. Particularly in microalbuminuric (hyperfiltering) patients, GFR is significantly underestimated with wide limits of agreement by the MDRD equation as well as by the Cockcroft-Gault formula.

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Thirty-seven fourth-year students underwent standardized patient training in death disclosure during a fourth-year emergency medicine clerkship. Practical applications of probiotics include their use in anti-tumour and anti-allergy immunotherapy, but there is also increasing evidence that some probiotics can stimulate a protective immune response sufficiently to enhance resistance to microbial pathogens.

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In contrast, duodenal injection of cholestyramine post irradiation to bind bile acids had no effect on survival time or diarrhea incidence. On cutaneous (6 linear and 5 angular parameters) and bony (5 linear and 4 angular parameters) facial profile of young adults, sexual differences were studied by discriminant analysis. Policosanol is a natural mixture of higher aliphatic primary alcohols. The validity and clinical role of currently available objective methods for the assessment of opioid abstinence in neonates and older infants are defined.

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It appears that in this disease the migrating granule cells mature too early and become arrested in the molecular layer, because of their abnormal forms, while others continue to migrate and grow in size in their normal location in the inner granule-cell layer. The macroscopic shape changes of the zebrafish yolk cell, as well as the morphogenetic movements of its YSL nuclei, are homologous to several morphogenetic behaviors that are regionally expressed within the vegetal endodermal cell mass of gastrulating Xenopus embryos. In addition, a mutant that was defective in all of the mbrABCD genes and rgpA was more sensitive to bacitracin than either the RGP or Mbr mutants. Inhibitory responses at the lowest concentration of EtOH (200 mg/100 ml) occurred inconsistently.

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ORIGIN AND REGRESSION OF PULMONARY VASCULAR DISORDERS AFTER INDUCED EXPERIMENTAL AIR EMBOLISM Our data support a common evolutionary origin for the GPs of Ebola virus and avian retroviruses and have implications for gene transfer mediated by Ebola virus GP-pseudotyped retroviruses. The impact of new knowledge coming from the field of genomics will be large. Stimulation of actin synthesis by cytochalasin D is specific for the isoactins normally expressed in muscle or non-muscle cells.

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induced a marked respiratory depression and irregular breathing which could be prevented or antagonized by administration of theophylline. Influence of body position on diaphragmatic and scalene activation during hypoxic rebreathing.

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High concentrations (greater than 10 pmol/g wet tissue) were present in bovine lung, rumen, trachea, aorta, uterus and stomach. The depression was not restored in vitro after treatment with dithiothreitol and zinc. While standardized approaches to empiric therapy with early inclusion of antibiotics active against Gram-positive organisms and against fungi may have improved the outcome of these patients during the past decade, other developments (e.g. The displacement constraints are then derived from the correspondence relationship.

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We found that with moderate currents, cortical spikes were evoked with low to moderate probability and their occurrence was modulated by ongoing sensory (visual) input. We found that the plasma levels of TM were significantly elevated in preeclamptic women vs. One-step surgery for WPW syndrome complicated with aortic stenosis Knowledge of the binding mechanism will be important for the generation of either IL-4 or IL-13 specific drugs.

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Histologic changes in resected and reimplanted autologous septal cartilage and bone following crush injury Achievement of in utero retention of calcium and phosphorus accompanied by high calcium excretion in very low birth weight infants fed a fortified formula. Although many GM inoculants have been developed and tested under laboratory conditions, commercial exploitation has lagged behind. Our results demonstrate that, in contrast to other studies of ligand-gated ion channel receptors, agonist- and antagonist-binding sites are composed of distinct amino acid residues.

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Using epidemiological studies to check the consistency of the cancer risks predicted by high-dose animal experiments: a methodological review. Invasive pulmonary aspergillosis in an infant: an unusual presentation of chronic granulomatous disease. The increasing subspecialization of general surgeons in their elective work may result in deskilling and create problems in providing expert care for emergency cases.

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Women with breast cancer undergoing adjuvant or neoadjuvant chemotherapy gain weight, whereas metastatic cancer patients will probably lose weight during palliative chemotherapy. The 7-cm-sized tumor consisted of two different components: a fibrosarcoma and a benign cystic teratoma. Following 2-3 days of coronary ligation, ANP immunoreactivity was detected in the viable myocardium of the lateral border of the infarct and in a few layers of viable cardiac myocytes located in the subendocardial areas of the ischemic left free ventricular wall.

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Portions of all of the specimens were fixed in formalin and embedded in paraffin and plastic for hematoxylin-eosin and periodic acid-Schiff staining. However, until recently, there was little international cooperation in trying to find solutions to the problem. We present results from an experimental study of the beam halo in a high-current 6.7-MeV proton beam propagating through a 52-quadrupole periodic-focusing channel. Therapeutic plans for the management of HPV infections by topical application of interferon-alpha.

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The metal inlay acted rigidly beyond a thickness of approximately 5 mm. SOCS1 regulates interferon-gamma mediated sensory neuron survival.

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The ELISA optical density readings obtained in the procedure were used as a screening indicator for selection of samples for further culture examination, and the selective culture methods examined to assist strain isolation did have potential. One key to understanding motivated behavior is examining the behavior of individuals as they work on multiple tasks under a time constraint. The results obtained using this technique in four clinical cases are presented here. During fasting measured powers were relatively low and reproducible. Three cases of advanced ulcerating basal cell gold daric coin for sale carcinoma (terebrant ulcer or ulcus terebrans) of the head are reported.

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Global gene expression profiles of the cyanobacterium Synechocystis sp. Pretibial myxedema and high-dose intravenous immunoglobulin treatment. This case presents many of opiate drugs have the effect of climate the typical features of parathyroid cysts.

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