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Aklovir (Acyclovir)

Aklovir is an antiviral drug, a synthetic nucleoside analogue, that has inhibitory activity (interferes with viral replication) against the herpes viruses, including herpes simplex 1 and 2 (cold sores and genital herpes), varicella-zoster (shingles and chickenpox), and Epstein-Barr virus (mononucleosis). Viruses take over living cells and reproduce themselves, often at the expense of the host cell. The Aklovir is converted to an active form by the virus itself, and the virus then uses the active form of Aklovir rather than the nucleoside it normally uses to manufacture DNA, a critical component of viral replication. Incorporation of active Aklovir into new viral DNA stops the production of the DNA. Virally infected cells absorb more Aklovir than normal cells and convert more of it to the active form, which prolongs its antiviral activity. The FDA approved Aklovir in March 1982.

Other names for this medication:
Acyclovir, Abduce, Acic, Aciclobeta, Aciclomed, Aciclostad, Aciclovirum, Acifar, Acihexal, Aciklovir, Acitop, Acivir, Acivirex, Acivision, Acix, Actios, Activir, Acycloguanosine, Acyl, Acyrax, Acyvir, Aklovir, Antivir, Asiviral, Avir, Aviral, Avix, Avorax, Blistex, Cicloferon, Cicloviral, Clinovir, Clirbest, Clopes, Clovate, Clovir, Cusiviral, Cyclomed, Cyclovax, Cyclovex, Cyclovir, Danovir, Declovir, Epsin, Eurovir, Hascovir, Hernovir, Herperax, Herpesil, Herpesin, Herpex, Herpin, Herplex, Heviran, Immunovir, Lisovyr, Lovir, Lovire, Lovrak, Medovir, Menova, Ocuvir, Poviral, Ranvir, Remex, Rexan, Scanovir, Sitavig, Sophivir, Soviclor, Supraviran, Telviran, Uniplex, Vilerm, Viraban, Viralex, Viratac, Viratop, Virest, Virestat, Virex, Virless, Viroclear, Virolex, Viromed, Virosil, Virostatic, Virovir, Virucid, Viruderm, Virustat, Virux, Vivorax, Xiclovir, Xorox, Zevin, Ziverone, Zoral, Zorax, Zoraxin, Zovirax,

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Aklovir is also sometimes used to treat eczema herpeticum (a skin infection caused by the herpes virus) to treat and prevent herpes infections of the skin, eyes, nose, and mouth in patients with human immunodeficiency virus (HIV), and to treat oral hairy leukoplakia (condition that causes hairy white or gray-colored patches on the tongue or inside of the cheek).

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

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The most important pathway for the catabolism and excretion of cholesterol in mammals is the formation of bile acids. Surprisingly, there were no significant differences in the levels of the oxidation products in the ascorbate-deficient and -replete Gulo(-/-)mice.

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The anticipated of phase III study is to evaluate the clinical usefulness of anticancer drug in terms of effectiveness and toxicity. The assessment in RA included clinical characteristics, disease activity (RADAR), functioning (HAQ-Di and global functional status), comorbidity, and radiological damage. The characteristic kidney-shaped cross-sectional model was created using a parametric equation.

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To exclude blocking of binding epitopes by labeling on recombinant CRP, biotinylation was performed at various biotin to protein ratios. The HCV RNA positive rate was 2.5 per thousand (146/56,000) and none of the patients followed up suffered from HCV infection.

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Surveys conducted in several countries corroborate the wellknown fact that a large proportion of old-age people take drugs (frequently different types at the same time). It has been proposed that this recombination converts chromosome multimers formed by homologous recombination back to monomers in order that they can be segregated prior to cell division.

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Identification and evaluation of free radicals in the sequence cardiac ischemia-reperfusion Mutations causing aminotriazole resistance and temperature sensitivity reside in gyrB, which encodes the B subunit of DNA gyrase. Since the different solubility characteristics of CFC-11 and deltaDIC(ant) cause major differences in their oceanic uptake features, indicating different uptake pathways, a care should be taken while assessing deltaDIC(ant) in the oceans relying on CFC-11 concentrations.

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Physician assisted suicide and voluntary euthanasia: some relevant differences. When sonography was inconclusive, CT amniography confirmed a single amniotic cavity, permitting appropriate parental counseling and pregnancy management.

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The beta gamma-mediated membrane localization of beta ARK serves to intimately link receptor activation to beta ARK-mediated desensitization. Two Polypeptides in the Inner Chloroplast Envelope of Dunaliella tertiolecta Induced by Low CO(2). CB3717 retains activity against transport-defective MTX-resistant cells, and also against cells that overproduce DHFR. These findings strongly suggest that the HIV-1 MA domain of HIV-1 Gag is responsible for the assembly defect in mouse cells. The beam-walking task and the Lashley maze are robust and sensitive methods in detecting sensorimotor and cognitive impairment after TBI in rats, respectively.

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A region of feline immunodeficiency virus (FIV)/Glasgow-8 external envelope glycoprotein (env) incorporating the third and fourth variable regions (V3/V4) was cloned, inserted into the pGEX vector and expressed in Escherichia coli to yield milligram quantities of the recombinant polypeptide as a fusion protein with glutathione S-transferase. Inhibition of N-nitrosodimethylamine metabolism by ethanol and other inhibitors in the isolated perfused rat liver. In stromal dystrophies, PTK was effective in removing large subepithelial stromal plaques.

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A method for the quantitative analysis of N-oxalylcysteine and oxalyl thiolesters (RSCOCOO-) in biological samples is described. This basic property affects their digestion, absorption, and transport in the blood and metabolism at cellular level.

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