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Avorax (Acyclovir)

Avorax is an antiviral drug, a synthetic nucleoside analogue, that has inhibitory activity (interferes with viral replication) against the herpes viruses, including herpes simplex 1 and 2 (cold sores and genital herpes), varicella-zoster (shingles and chickenpox), and Epstein-Barr virus (mononucleosis). Viruses take over living cells and reproduce themselves, often at the expense of the host cell. The Avorax is converted to an active form by the virus itself, and the virus then uses the active form of Avorax rather than the nucleoside it normally uses to manufacture DNA, a critical component of viral replication. Incorporation of active Avorax into new viral DNA stops the production of the DNA. Virally infected cells absorb more Avorax than normal cells and convert more of it to the active form, which prolongs its antiviral activity. The FDA approved Avorax in March 1982.

Other names for this medication:
Acyclovir, Abduce, Acic, Aciclobeta, Aciclomed, Aciclostad, Aciclovirum, Acifar, Acihexal, Aciklovir, Acitop, Acivir, Acivirex, Acivision, Acix, Actios, Activir, Acycloguanosine, Acyl, Acyrax, Acyvir, Aklovir, Antivir, Asiviral, Avir, Aviral, Avix, Avorax, Blistex, Cicloferon, Cicloviral, Clinovir, Clirbest, Clopes, Clovate, Clovir, Cusiviral, Cyclomed, Cyclovax, Cyclovex, Cyclovir, Danovir, Declovir, Epsin, Eurovir, Hascovir, Hernovir, Herperax, Herpesil, Herpesin, Herpex, Herpin, Herplex, Heviran, Immunovir, Lisovyr, Lovir, Lovire, Lovrak, Medovir, Menova, Ocuvir, Poviral, Ranvir, Remex, Rexan, Scanovir, Sitavig, Sophivir, Soviclor, Supraviran, Telviran, Uniplex, Vilerm, Viraban, Viralex, Viratac, Viratop, Virest, Virestat, Virex, Virless, Viroclear, Virolex, Viromed, Virosil, Virostatic, Virovir, Virucid, Viruderm, Virustat, Virux, Vivorax, Xiclovir, Xorox, Zevin, Ziverone, Zoral, Zorax, Zoraxin, Zovirax,

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Avorax comes as a tablet, a capsule, and a suspension (liquid) to take by mouth. It also comes as a delayed-release buccal tablet to apply to the upper gum of the mouth. The tablets, capsules, and suspension are usually taken with or without food two to five times a day for 5 to 10 days, starting as soon as possible after your symptoms begin. When Avorax is used to prevent outbreaks of genital herpes, it is usually taken two to five times a day for up to 12 months. The delayed-release buccal tablet is usually applied with a dry finger as a one-time dose within 1 hour after itching, redness, burning or tingling cold sore symptoms begin but before the cold sore appears. Take or use Avorax at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take or use Avorax exactly as directed. Do not take or use more or less of it or take it more often or for a longer time than prescribed by your doctor.

Do not chew, crush, suck, or swallow the delayed-release buccal tablets. Drink plenty of liquids, if you have a dry mouth while using the delayed-release buccal tablets.

To use buccal Avorax, follow these steps:

  1. Find the area on the upper gum above your left and right incisor teeth (the teeth just to the left and right of your two front teeth).
  2. With dry hands, remove one delayed-release tablet from the container.
  3. Gently apply the tablet to the upper gum area as high as it will go on your gum above one of your incisor teeth on the side of your mouth with the cold sore. Do not apply it to the inside of the lip or cheek.
  4. Hold the tablet in place for 30 seconds.
  5. If the tablet does not stick to your gum or if it sticks to your cheek or the inside of your lip, reposition it to stick to your gum. Leave the tablet in place until it dissolves.
  6. Do not interfere with the placement of the tablet. Check to see if the tablet is still in place after eating, drinking, or rinsing your mouth.

If the delayed-release buccal tablet comes off within the first 6 hours of application, reapply the same tablet. If it still will not stick, then apply a new tablet. If you accidentally swallow the tablet within the first 6 hours of application, drink a glass of water and place a new tablet on your gum. If the tablet falls off or is swallowed 6 or more hours after application, do not apply a new tablet until your next regular time.

Avoid the following while you are using Avorax buccal delayed-release tablet:

  • Do not chew gum, touch, or press the buccal tablet after it has been applied.
  • Do not wear upper dentures.
  • Do not brush your teeth until it dissolves. If your teeth need to be cleaned while the tablet is in place, rinse the mouth gently.

Shake the suspension well before each use to mix the medication evenly.

Your symptoms should improve during your treatment with Avorax. Call your doctor if your symptoms do not improve or if they get worse.

Take or use Avorax until you finish the prescription, even if you feel better. If you stop taking Avorax too soon or skip doses, your infection may not be completely treated or may become more difficult to treat. The delayed-release buccal tablet is applied as a one-time dose.

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ALA significantly increased ROS, and this effect was blocked by N-acetyl-cysteine, which also inhibited ALA-induced activation of p44/42 mitogen-activated protein kinase (MAPK) and AP-1, HO-1 expression, and HO activity. The sensitivity limit is approximately 1 ng of estazolam in a 1-ml sample. On the basis of the structure of H-Ras in complex with the catalytic domain of p120-GAP, we have developed a set of site-specifically labelled Ras-variants, one of which turned out to be particularly sensitive for studying the interaction with Ras-specific GAPs. The effect of different pine hosts on the sampling of Rhizopogon spore banks in five Eastern Sierra Nevada forests. A protective effect of skimmed milk and artificial sweeteners was also observed.

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Molecular diversity of neuronal-type calcium channels identified in small cell lung carcinoma. Place of cognitive-behavioral therapies in resistant depressions

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The presence of a single plasmid 8.5 kb in size has been demonstrated in a cholesterol biotransforming strain of Micrococcus. We assessed 73 renal/bladder ultrasounds and 7 autopsies performed between 1998 and 2000 for renal and bladder malformations. Such a debate would be a significant first step towards the implementation of policies which reflect the opinion of the entire community rather than just the professionals who provide the service, or sectional groups who manage to influence the professionals.

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In flow cytometric analyses 2C5 and 4A2 bound to B cell populations in the peripheral blood and lymphoid organs. Duodenogastric reflux on (99m)Tc-tetrofosmin myocardial SPECT mimics left ventricle inferior wall reverse redistribution and falsely decreases ejection fraction: a case report.

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Effect of community-wide use of insecticide-treated nets for 3-4 years on malarial morbidity in Tanzania. In the case of post-phlebitic syndrome, the average index is 101 and 102 mmHg in the deep and superficial veins. Occurrence of antibodies against hepatitis C virus (HCV) among alcoholics In two patients with a left ventricular assist system, a defined, sudden 1 L/min change in cardiac output was carried through to evaluate the in vivo response time of the continuous cardiac output monitoring system.

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Salvianolate inhibits proliferation and endothelin release in cultured rat mesangial cells. Induction of spermatogenesis in patients with non-obstructive azoospermia after antegrade sclerotherapy Possible benefits to participants are increased longevity, decreased risk of cardiovascular disease, improved psychological well-being, and greater fitness.

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A light-weight, inflatable habitat module called TransHab was built and shown to provide adequate protection against micrometeoroid impacts and good shielding properties against charged particle radiation in the International Space Station orbits. With the recent finding that p50(cdc37) is tumorigenic in transgenic mice, these results reinforce the intriguing observation that the family of heat shock proteins represents a novel class of molecules with oncogenic potential.

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Dynamics of the saliva antipyrine content in women throughout the period of pregnancy was studied. In liver cirrhosis, however, they significantly decreased in number. We report the 11th well-documented case of laryngeal rhabdomyosarcoma and only the second of laryngeal alveolar rhabdomyosarcoma. Antiviral and antitumoral effects of recombinant chicken myelomonocytic growth factor in virally induced lymphoma. The present study used an LPS rat model to investigate the role of oxidative stress in spermatogenesis.

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This study analyzed the microbiology of bile and the antibiotic sensitivities of the organisms identified in patients presenting with clinical cholangitis or cholestasis. Despite intensive medical care, death occurred 10 days later due to malignant cerebral edema. Risk behaviors of Filipino methamphetamine users in San Francisco: implications for prevention and treatment of drug use and HIV. Ernest Henry Starling--the scientist, the educator, and the fundamental law of the heart

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The nature of this inhibition suggested the presence of an allatostatin specific for the synthesis of JH I. Characterization and isolation of a high-density-lipoprotein-binding protein from bovine corpus luteum plasma membrane. This is a time-consuming process, and has the inevitable effect of slowing down project work. Development and in vitro evaluation of an enteric-coated multiparticulate drug delivery system for the administration of piroxicam to dogs.

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Overestimation of the numbers of chronic carriers of Salmonella typhi in Santiago. Endoscopy for upper gastrointestinal bleeding at emergency unit.

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We used receiver operating characteristic (ROC) analysis to compare two methods of evaluating observer performance in detecting an abnormality on chest radiographs. Substrate specificity of methylthioadenosine phosphorylase from human liver. Different possibilities of coordination between circulation, respiration and abdominal movements were found in pupae of Pieris brassicae, Tenebrio molitor, Galleria mellonella and Leptinotarsa decemlineata. Recent clinical studies have shown that early treatment with sumatriptan when migraine pain is mild is more effective than sumatriptan treatment when pain is moderate to severe.

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Hepatitis B immunoglobulins blocking hepatitis B virus infection of trophoblast cell culture in vitro We assume that BX was produced after translation by cleavage of the mature protein or the AX molecule with streptococcal proteinase (ETB) or an arginylaminopeptidase which is detectable on whole cells. SEPARATION OF FREE AND BOUND INSULIN IN BLOOD PLASMA ON ION EXCHANGE RESINS Individual variations in patellar tendon anatomy should be considered when choosing the proper entry site for tibial nailing. Regression analysis of the preload recruitable stroke work slope revealed a significant intervention effect independent of the method used.

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Human breast sarcoma and human breast implantation: a time trend analysis based on SEER data (1973-1990). LVBG was performed in patients who refused laparoscopic banding because of port waar valt action ondertiteling placement and adjustment, or in patients with hiatus hernia, with or without gastroesophageal reflux disease.

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In 4 experiments, the authors investigated the time course of semantic priming effects during 2 forms of visual word identification, lexical decision and pronunciation. Reoperative aortic procedures after CABG can be performed safely with myocardial protection via hypothermic perfusion of a patent in-situ arterial graft. A post mortem examination of a 70 year old man, who died three years after a poorly differentiated adenocarcinoma of prostate had been diagnosed, showed widespread signet-ring cell carcinoma, with an associated linitis plastica. To determine paralisia bell acyclovir ointment the frequency and natural course of mediastinal masses in asymptomatic people at high risk for lung cancer who were undergoing computed tomographic (CT) screening. Bioweapons treaty in disarray as US blocks plans for verification.

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The arthritis appeared first as a relapse of a series of hemarthroses . Evaluation of the stereoselective metabolism of the chiral analgesic drug etodolac by high-performance liquid chromatography. Search for maternal cells in human umbilical cord blood by polymerase chain reaction amplification of two minisatellite sequences. Examples of novax side effects both types of theory are briefly described, and irrelevant and relevant evidence is critically discussed. Patterning in rapidly evaporated polymer solutions: formation of annular structures under evaporation of the poor solvent.

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The purpose of interventions for chronically hospitalized cognitively impaired patients does not appear to have been considered adequately, and it is concluded that future research will be hampered unless greater consideration is given to information processing theory relating to amnesia. The present study focused on 2 issues: which proximate determinant of fertility is most important in Puerto Rico and whether the conmy tablet importance of the proximate determinants differs across education groups.

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How can we make our medical students enthusiastic about a future in obstetrics and lawrence marable tenormin dose gynaecology? The urticaria was not adequately controlled by antihistamines or Prempak-C (conjugated oestrogens and norgestrel). Secondary right hemiplegia associated with a confused state justified emergency hyperbaric oxygen therapy, which was followed by complete neurological recovery. Addressing issues of autonomy, beneficence, nonmaleficence, truth-telling, confidentiality, and justice are important in caring for African American elders.