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Cardizem (Diltiazem)
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Diltiazem

Tetracyclic derivatives of Cardizem from aurones and thioaurones Although Cardizem moderately inhibited the rise in plasma IR-ET-1 and potassium concentration in these mice, it did not affect the accumulation of IR-ET-1 in the heart, lung or kidney. In conclusion, long-term treatment of SHR with Cardizem may protect the myocardium when myocardial ischemia occurs.

Other names for this medication:
Diltiazem, Cardizem,

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OTHER This medication may also be used for chest pain (angina) or high blood pressure.

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The treatment of mastocytoma cells with 8-methoxypsoralen and long-wavelength ultraviolet radiation enhances cellular immunogenicity: preliminary results. Many countries have implemented managed care techniques, which are driven by policy efforts to increase quality or to control costs.

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Parameters correlating to cytoplasmic activation of the nuclear transcription factor NFkappaB (intracellular calcium mobilization), to nuclear translocation of the NFkappaB p65 subunit and to mRNA-transcription of inflammatory cytokines known to be expressed upon exogenous LPS-stimulation and to require NFkappaB activation (interleukin-1beta, interleukin-6, tumor necrosis factor alpha) were investigated. Botanical medicines for the treatment of cancer: rationale, overview of current data, and methodological considerations for phase I and II trials. Although the mechanism of increased clearance in pathological states is not known, the 99mTc-DTPA lung-clearance technique has great potential clinically, particularly in patients at risk from ARDS and HMD and in the diagnosis and follow-up of alveolitis. Novel genes regulated by Sonic Hedgehog in pluripotent mesenchymal cells. To assess the efficacy and safety of lowering dietary intake of total fat, saturated fat, and cholesterol to decrease low-density lipoprotein cholesterol (LDL-C) levels in children.

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To explore the putative causal link between Hox expression and craniofacial morphology, we produced a specific series of bilateral crest deletions in chick embryos and assessed branchial arch morphology, Hox gene expression, and patterning of skeletal structures in the postoperative embryo. 3 of these volunteers were also given tetracycline hydrochloride every 6 h for 5 days either 1 month before or after doxycycline administration to compare gingival fluid levels of these 2 tetracycline compounds.

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The results of this study show an inverse association of measures of body fat distribution and total fat mass with serum iron level in Hispanic women. SDS-PAGE and REA indicated considerable homology among MS reference strains and recent field isolates. In the selected patients with metastatic lung tumors, surgical treatment can be conducted with a reasonably good result, even though the metastatic malignancy is multiple or bilateral.

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Trophoblasts derived from two first-trimester placentae bound more prourokinase than cells isolated from term placentae. This method of the replacement of blood should be considered for patients who are to undergo a major orthopaedic procedure on the hip. A specific interaction between NADPH-cytochrome reductase and phosphatidylserine and phosphatidylinositol.

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All patients were infected with S mansoni and had schistosomal hepatic fibrosis and ascites. From July 1999 to August 2000, all cirrhotic in-patients presenting with upper gastrointestinal bleeding but without infection were enrolled. Correction of exorbitism remained stable in all but one patient, who required a second advancement of the orbital segment. The somatic, psychic, social, professional, and family problems due to the tumour and its therapy have to be eliminated, improved or prevented.

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RPI is similar to elastase in its substrate specificity and has a lectin-like affinity for mannose. Laparoscopic ultrasound examination of the bile duct is superior to operative cholangiography and could replace it. FISH analysis of replication and transcription of chromosome X loci: new approach for genetic analysis of Rett syndrome.

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Until recently, visualization of the coronary arteries was the sole domain of catheter-based x-ray angiography. Myocardial metabolic changes during reperfusion of ventricular fibrillation: a 31P nuclear magnetic resonance study in swine. Antibody response to myelin oligodendrocyte glycoprotein and myelin basic protein depend on familial background and are partially associated with human leukocyte antigen alleles in multiplex families and sporadic multiple sclerosis. To investigate the validity of transcutaneous measurements of blood gas tensions for the assessment of partial arterial pressure of oxygen (PaO(2)) and carbon dioxide (PaCO(2)) during treadmill exercise.

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EXPERIMENTAL CHRONAXIMETRIC STUDY OF SEVERAL ISOTROPIC AGENTS AND OF THEIR ACTION ON THE NERVOUS EFFECTS OF ETHYL ALCOHOL. Popliteal vein compression caused by popliteal cyst was detected in 53-year-old man with venostasis of the lower limb.

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38 cases had posttraumatic osteitis, in eight the defect was merely a soft tissue defect and in three due to tumour excision. Gene jun was expressed from a lacZ promoter as a fusion protein with the viral coat protein, pIII, thereby being structurally incorporated into phage particles during infection with a helper phage. Genetic variability may determine which of these pathways, or possible other pathways, predominate in an individual following immunization.

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A review of the literature showed that six cases of congenital midline porencephaly have been reported, though none had sonographic evaluation in the prepartum period. Light microscopic and EM examination revealed that in the denervated skin the regenerating axons utilized the same dermal perineurial pathways followed by collaterally sprouting axons. In the American literature, exemplified by DSM-III, greater emphasis is placed on symptomatic classification and panic is given separate diagnostic status, both alone and in conjunction with agoraphobia. Freeze-fracture cytochemistry with the cholesterol-binding antibiotic filipin has been used to examine the plasma membrane of uterine epithelial cells at different stages of pregnancy in the rat.

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The biological changes of NIH3T3 cells co-cultured with human bone morphogenetic protein-2 gene transfecting cells Immunocytochemistry with antibody to parvalbumin was used to specifically label relay neurons connecting to the visual cortex.

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Positive cytology findings as well as other evidence of disseminated disease may indicate that gastrectomy should be avoided. Hypertonic saline as a resuscitation solution in hemorrhagic shock: effects on extravascular lung water and cardiopulmonary function. The increase in electromotility is partially mediated by a calmodulin-dependent mechanism, since W7, a calmodulin antagonist, attenuated the 50 microM ionomycin-induced motility increase.

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Despite this type of evidence, there is a lack of data concerning the effects of Mg supplementation in the aged. A new combination ointment has been formulated, which contains both calcipotriol and the corticosteroid betamethasone dipropionate.

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Case report: complex arrhythmia induced by noncompetitive atrial pacing algorithm of DDDR pacemaker. Genome-wide analysis of mammalian promoter architecture and evolution. One case of mixed carcinoid/adenocarcinoma and 5 cases of endocrine carcinomas, 4 poorly and 1 moderately differentiated, were also identified. By including additional tests some patients may benefit in respect of safety and better knowledge of the underlying mechanisms. Mini-abortion, the determination of its effectiveness and the present method of performing it at the Institute for Maternal and Child Care

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During the 42nd week, dilatation followed by mitomycin C application stabilized the right lung function. Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretion.

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The biological activity of SVNF, in contrast to that of NGF, is partially retained after preparative sodium dodecyl sulfate-polyacrylamide gel electrophoresis and can be electrophoretically eluted with an apparent molecular weight of 16-20 kilodaltons. Identification of mechanisms responsible for increase of BP in childhood will improve prevention of hypertension in adulthood.

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Pressures were measured simultaneously at three different sites in the muscle by a catheter-tip transducer with extremely low volume-displacement characteristics and by two extracorporeal transducers connected to slit catheters. PGE2 regulates cAMP production in cultured rabbit CCD cells: evidence for dual inhibitory mechanisms. Using overiectomized female rats, we also examined the effects of seven days of estradiol and/or progesterone replacement.

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Intelligence and personality profile of battering parents in Greece: a comparative study. Stationary-table MR angiography is a useful, simple strategy for lower extremity angiography in centers without a moving table. Thus, in hepatocytes as in other cell lines, all three FKHR PKB sites participate in insulin-mediated inhibition of FKHR action and in insulin-mediated accumulation of FKHR in cytoplasm. A novel intermediate on the import pathway of cytochrome b2 into mitochondria: evidence for conservative sorting.

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Variation of 1,6-diphenyl-1,3,5-hexatriene lifetime distributions by multifrequency phase and modulation fluorimetry. Mitotic figures were observed in many mast cells during the period numbers were increasing.

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A thorough understanding of the molecular basis for substrate and inhibitor specificity is critical to defining mechanisms of evasion by drug-resistant mutants as well as for the rational design of drugs able to inhibit a broad spectrum of HIV-1 variants. Women, thrombolytic therapy, and the gender gap: recommendations for practice.

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Finally, these principles are applied in the discussion of a number of specific drugs frequently prescribed in the emergency department setting. Of the three major cytoskeletal filament systems, the intermediate filaments are the least understood. Inner-retinal contributions to the photopic sinusoidal flicker electroretinogram of macaques.

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The aim of this study was to report the hearing results in surgically treated cases of stapes fixation. In shamoperated diabetic rats the aortic glucose oxidation was reduced after a diabetes duration of 4 days. Dietary gamma-linolenic acid dose-dependently modifies fatty acid composition and immune parameters in rats. We report two cases in the oral cavity, one in the soft palate and one in the tonsil. On the contrary, PI(4,5)P(2) must be dephosphorylated when they shed clathrin coats to fuse endosome.

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A case of cryptococcal meningitis with unilateral paresis of the superior division of the oculomotor nerve was reported. It is suggested that it may contribute to the forces involved in the movement of cells in the extracellular matrix in vivo especially during remodeling and embryogenesis. Randomized comparative trial of three monospecific antivenoms for bites by the Malayan pit viper (Calloselasma rhodostoma) in southern Thailand: clinical and laboratory correlations. The single disulfide bond in Escherichia coli thioredoxin was reduced by reaction with a 20-fold excess of reduced dithiothreitol at neutral pH and 25 degrees C. The spider-web fashion in the peripheral cytoplasm of the smooth muscle cells was observed in all animals.

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The TIME Project is using this technology to create engaging, believable clinical situations that promote experiential learning, discovery learning, and contextual instruction in the medical school classroom. to foetal liver cultures resulted in increased myeloid proliferation coupled to extensive myeloid differentiation. Quantitative evaluation of bone density using the Hounsfield index.

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A 52-year-old female presented with dyspnea, low back and widespread bone pain. Understanding alcohol misuse and comorbid psychiatric disorders. Lipocalin 2, haptoglobin, serum amyloid A3, stearoyl-CoA desaturase, and 11beta-hydroxysteroid dehydrogenase 1 were induced while actin alpha2 and procollagen VIII alpha1 were suppressed by adipocyte differentiation. All isolated patellar tendon injuries in the study had excellent function at followup. Model of the codon-anticodon complex and the reciprocal arrangement of 2 tRNA molecules on a ribosome

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Sternomastoid myoperiosteal flap for reconstruction of the subglottic larynx. No significant systemic toxicities were noted in the paclitaxel-treated animals.

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Activity of acidic granulocyte phosphatase and myeloperoxidase among women with EPH gestosis Neuropsychological predisposition to early acquisition of reading is suggested. A RNA-PCR method and different sets of primers were used to investigate the expression of different hepatitis B (HB) virus genes at the RNA level. Human cerebellar UBCs are numerous too, but auditory UBCs have escaped detection.

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As reliable data on prevalence rates of drug-induced oral mucosa side effects are scarce in the medical literature, a retrospective analysis of drugs as possible inducers in 173 in-patients with either minor or major type of erythema multiforme (EM) admitted to the Erlangen University Department of Dermatology from 1970 through 1981 was carried out. These differences were no longer observed at 12 and 18 months of age. D-serine, an endogenous synaptic modulator: localization to astrocytes and glutamate-stimulated release. It is of particular importance to note that most of these tests need to be processed in specialized central laboratories to ensure the best sensitivity and specificity.

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Stimulation by neurturin causes increased phosphorylation of extracellular signal-regulated kinases 1 and 2 in cultured chromaffin cells, and mitogenesis is prevented by inhibitors of their phosphorylation. These results show that co-ions play a more important role than counterions in determining EDL potential and interaction in an electrolyte solution, especially for systems with high co-ion valence and/or high surface potentials. We also discuss the sensitivity of our results to the spectrum of the radiation field incident on the foil, and the role of nonlocal thermodynamic equilibrium atomic kinetics in affecting the spectra. On the other hand, with the precise diagnosis the surgeon was able to perform thyroidectomy for thyroid cancer in the first operation. Accuracy and precision of perfusion lung scintigraphy versus 133Xe-radiospirometry for preoperative pulmonary functional assessment of patients with lung cancer.

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Factor infusion is effective, but transient due to the short half-life of Factor proteins. Blood samples were taken at baseline, after 4 and 5 weeks, after 3 months, and after 10 months. PRELIMINARY OBSERVATIONS ON THE THERAPEUTIC EFFICACY OF EPSILON-AMINO-CAPROIC ACID IN HEMORRHAGIC SYNDROMES DUE TO BLOOD PLATELET DEFECTS Quantitation and mapping of integrated human papillomavirus on human metaphase chromosomes using a fluorescence microscope imaging system.

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Protein kinase C-mediated serine phosphorylation directly activates Raf-1 in murine hematopoietic cells. Chorea in hemodialysis: Is chorea just a neurological syndrome or is it related to uremia or dialysis? The binding of all of these antibodies to protein fractions eluted from AcA 54 and Matrex gel blue A columns coincided with the phospholipase A2 activity in these fractions. Salmonella that reside in the phagocytic vacuole do not cause this early cell death and can trigger a macrophage death at a much later time point.

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The primary objective was to observe whether the normally close relationship between heart rate and log NE concentration in upset when heart rate at a given work load is increased by heat stress. Finally, methods for the labeling of nanoparticles with gamma-emitting radionuclides are presented, and results obtained in animal species are given. Labrea hepatitis--hepatitis B and delta antigen expression in liver tissue: report of three autopsy cases. More recent data indicate that this is probably a mutation hot spot in CDL1.

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DMDTP, however, was immediately present in urine after exposure and provided stronger support for organophosphate exposure than did blood ChE. 3), but removing the degeneracy by identifying a lensing object would tighten the constraints on the mass in MACHOs. The results showed that the new annuloplasty technique was promising, although a long-term result is yet to be seen. Inhibitors of angiotensin-converting enzyme (ACE) or beta isoforms of protein kinase C (PKC) are nephroprotective in diabetes mellitus. Rescue centers today form the logistic center of the flow of information.

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These completed operations included right colectomy (24/30), sigmoid colectomy (22/36), appendectomy (9/10), anterior resection (3/8), abdominoperineal resection (3/5), and left colectomy (1/2). Unfractionated inflammatory cytokines inhibit cAMP-induced Schwann cell expression of galactolipids (Gal). COMPENSATORY HYPERTROPHY OF RIGHT ADRENAL AFTER LEFT ADRENALECTOMY: OBSERVATIONS IN FETAL, NEWBORN AND WEEK-OLD RATS. A paradigm for studying relations between behavioral, neurochemical, and electrophysiologic processes is presented.

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Application of immunocorrective measures in disruption of adaptation processes improves the outcomes of CCT. The comparative perspective and choice of animal models in aging research. Gastric and duodenal obstruction in patients with cholangiocarcinoma in the porta hepatis: increased prevalence after radiation therapy. The expression of these operons is under the control of the repressor AllR.

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Consequently, conditions that result in consistent hyperopic defocus could potentially contribute to the development of juvenile onset myopia in children. In no case was the provisional clinical diagnosis correct, with working diagnoses ranging from abscess to neoplasm. The resonances of these cavities were fine-tuned in steps smaller than 2 nm by digital etching. Both morphology and quantification of the cutaneous microvasculature showed changes with site and age.

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In endotoxemia and septic shock, enhanced generation of endogenous nitric oxide (NO) contributes to myocardial depression, hypotension, and derangement of gas exchange. These data suggest that the SCN contains a large population of autonomous, single-cell circadian oscillators, and that synapses formed in vitro are neither necessary for operation of these oscillators nor sufficient for synchronizing them. We know that narcotic addiction takes a terrible toll and that, like alcoholism, we are currently unable to cure it. Ontogeny of 3H-muscimol binding to membranes of chick forebrain. Magnesium sulfate alone effectively controlled biseptol 480 mg sodium controlled convulsions in the great majority of cases.