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Lotim (Losartan)
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Losartan

Efficacy of manidipine/delapril versus Lotim/hydrochlorothiazide fixed combinations in patients with hypertension and diabetes. The present study was undertaken to test the effect of two angiotensin II type 1 (AT1) receptor antagonists, Lotim and irbesartan, on ATS-stimulated MCP-1 expression as well as glomerular influx of M/M.

Other names for this medication:
Losartan, Cozaar, Lortaan, Losacar, Losakind, Lostat, Omnitan, Losium, Angilock, Angizaar, Aratan, Araten, Cardon, Cartan, Cormac, Corodin, Corus, Cosart, Covance, Eklips, Etan, Fensartan, Fortzaar, Hilos, Lacine, Lara, Larb, Lavestra, Lifezar, Loben, Logika, Loortan, Lopo, Lorista, Losa, Losacor, Losan, Losap, Losaprex, Losar, Losart, Losartanum, Losartas, Losatan, Losatrix, Lostan, Lotan, Lotar, Lotim, Lozap, Lozar, Lyosan, Mozartan, Niten, Normatens, Ocsaar, Osartil, Ostan, Prelow, Prosan, Rasertan, Rasoltan, Repace, Resilo, Rosatan, Sarilen, Sarlo, Sarvas, Sarve, Simperten, Sortal, Sortiva, Tacardia, Tozaar, Xartan, Zaart, Zartan,

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Lotim is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Lowering blood pressure may reduce the risk of strokes and heart attacks.

Lotim is an angiotensin II receptor blocker (ARB). It works by blocking a substance in the body that causes blood vessels to tighten. As a result, Lotim relaxes the blood vessels. A lower blood pressure will increase the supply of the blood and oxygen to the heart.

Lotim is also used to decrease the risk of stroke in patients with high blood pressure and enlargement of the heart. It is also used to treat kidney problems in patients with type 2 diabetes and a history of hypertension.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet

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Of 27 patients, 14 had positive ovarian fluorescence, compared with zero of 24 normal cycling controls (P less than .001) and one of 22 postmenopausal controls (P less than .01). Data were collected using a pretested questionnaire which was filled by one of the authors. Pre- and postsynaptic muscarinic receptors have been characterized in the isolated trachea and ileal circular muscle of the guinea pig. Although increased throughout the range of values of LDL-cholesterol, apoB and apoA-I might be of greatest value in diagnosis and treatment in men and women who have common lipid abnormalities, but have normal or low concentrations of LDL-cholesterol. The highest increases in NK activity were found in lymphoid cells recovered from the lung, active treatments with Biostim significantly increasing the proportion of both target-binding cells and lytic conjugate-forming NK cells.

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High-resolution three-dimensional magnetic resonance (MR) microscopy identified hypointense regions at the same position as in vivo. Surprisingly, we find that the high density clustering of Kv1 channels and Caspr2 at juxtaparanodes is normal in a mutant mouse lacking juxtaparanodal PSD-95, and that the indirect interaction between Kv1 channels and Caspr2 is maintained in these mutant mice. The idea that the electronic transition drives the transition in hematite is therefore invalidated.

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Activation of the proto-oncogenes c-myc and ras has been observed during malignant progression, but their role in tumour initiation remains unproven. No other adverse effects on reproduction, fertility and postnatal development were observed. Use of the microelectrode method for differentiation of white matter from thalamic nuclei during stereotaxic procedures

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Excimer laser coronary angioplasty involves the use of a pulsed, 308-nm ultraviolet laser transmitted by optical fibers to reduce coronary stenoses. The reduction of nitroxides was measured on intact luminal surfaces of gastric, intestinal, and urinary bladder mucosa, as well as in homogenates of mucosa surface layer. An increase in the plasma concentrations of prostaglandins (PGs) is associated with uterine contractile activity and with oviposition in the hen. A new method of tubal occlusion for sterilization, which is both promising and potentially reversible, is undergoing clinical trials nationwide. Ipsilateral thrombosis in the popliteal veins or thigh was seen in 11 per cent of the patients with unilateral total knee replacement, and contralateral thrombosis was noted in 3 per cent.

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We present a child with a unique anatomical variant of this anomaly, namely double ectopic thyroid. The interaction epitope could be narrowed down to residues Glu1251, Lys1252, and His1257 located in the C-terminal pore loop in domain 3. This observation warrants attention from the regular users of these plants because regular use of plants with tumour-promoting activity could well be an aetiological factor for the promotion of tumours among rural Malaysian Malays.

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Factors related to cigarette smoking and to changes over two years were investigated in a sample of Michigan adults. In contrast, there was no expression of CK19 in Chang liver cells or 2 of 5 hepatocellular carcinoma cell lines. Structure and reactivity of mixed alkali metal alkoxide/aryloxide catalysts.

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The results revealed denervation of the infraspinatus and approximately a 22 per cent loss of strength of the affected arm during external rotation. Seasonal reproduction in tropical reptiles might be driven by biotic factors (e.g., peak periods of predation on eggs or hatchlings, or food for hatchlings) or abiotic factors (e.g., seasonal availability of suitably moist incubation conditions). Data were recorded from 20 adult mechanically ventilated patients. However, no large studies on the efficacy and safety of Buc in RA patients have been published in English to date. While incidental masses in certain organs have received particular attention, periampullary and pancreatic incidentalomas (PIs) remain poorly characterized.

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High risk of developing toxoplasmic encephalitis in AIDS patients seropositive to Toxoplasma gondii. Cloning and expression of a cDNA for mu-class glutathione S-transferase from rabbit liver. Insufficiency of compensatory-adaptation reactions and lowered resources were revealed in the patients with a decreased tolerance to physical exercise. These results are consistent with the view that the increased risk of generalized-onset unprovoked seizures reflects a predisposition to both simple febrile convulsions and generalized-onset unprovoked seizures.

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Transformation of a continuous rat embryo fibroblast cell line requires three separate domains of simian virus 40 large T antigen. pylori-specific RAST analysis, specific IgE was found only in 1 of 25 H. Since Sos binds to the SH3 domains of Grb2 and thereby associates with Ras at the cell membrane, formation of the PI 3-kinase.Grb2.Sos complex provides a potential mechanism for growth factor-induced interactions of PI 3-kinase and Ras. Both are present in low amounts in the G(1) phase and exhibit increased abundance in the S and G(2) phases. The sensitive detection of human cells in immunodeficient rodents is a prerequisite for the monitoring of micrometastasis of solid tumours, dissemination of leukaemic cells, or engraftment of haematological cells.

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Asymptomatic perforation of the esophagus after C6/C7 plate osteosynthesis Sixty two male patients with polar leprosy--38 lepromatous and 24 tuberculoid types were investigated for the presence of antispermatozoal antibodies with special reference to their morphological patterns. Benefits and risks of modifying maternal fat intake in pregnancy and lactation. However, any dose of HPD could not ameliorate the established MAP sensitization. Mechanisms of cellular iron acquisition: another iron in the fire.

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The anatomic form and function of the human temporomandibular joint is compared with the monkey (Macaca and Papio) and goat joint. Improvements in surgical technique and an ever improving understanding of the embryologic and cellular origin of many congenital anomalies marks the gains made during the last decade in pediatric plastic surgery.

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Changes of immunological and cytogenetic indexes in lymphocytes of patients with bacterial endocarditis under the influence of laser therapy and a hyperbaric oxygen therapy Action of phorbol myristate acetate (PMA) at fertilization of mouse oocytes in vitro. Organization of a clinical information center on psychotropic drugs Colocalization in a CVH Px110 cell line of ICL with either endogenous catalase or with stably expressed CAT-PMP20/AKL (chloramphenicol acetyltransferase with a C-terminal-appended 12 amino acids ending with Ala-Lys-Leu) demonstrated targeting of ICL to peroxisomes. Anterior and oblique lateral views of the breasts were acquired 0-4 min, 10-20 min and 2 hr after intravenous injection of 740 MBq of 99mTc-MDP in 200 women with elevated suspicion or proven diagnosis of breast cancer (Group 1) and in 80 women with other solid tumor types (Group 2).

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Fluorescence microscopy was used to evaluate the biodistribution of doxorubicin in cell cultures (human Sk hepatoma and colon carcinoma). Effect of serum sources and colostral whey on bovine semen quality and spermatozoa immunoglobulin G immunofluorescence.

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The effects of three calcium antagonists (CA), nifedipine (NF), verapamil (V) and diltiazem (DL) on the enzyme-inducing activity of phenobarbital (PB) and beta-naphthoflavone (beta-NF) were measured by hexobarbital (HB) sleeping time, benzphetamine-N-demethylase (BND) ethoxycourmarin-O-deethylase (ECOD) and ethoxyresorufin-O-deethylase (EROD) activities, as well as by the cytochrome P-450 and cytochrome b5 content. The aim of this study was to investigate whether botulinum toxin (BTX) injection is an effective short- and long-term treatment for patients with symptoms caused by diffuse esophageal spasm. antisense treatment directed against the full-length trkB receptor (trkB.FL) attenuates carrageenan-induced hyperalgesia.

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SEPARATE FUNCTIONAL STUDY OF THE KIDNEYS IN THE EXPLORATION OF ARTERIAL HYPERTENSION This randomized, open-label, three-way crossover study in 12 healthy volunteers characterized the plasma pharmacokinetic parameter profiles of both drugs, as well as the white blood cell uptake and exposure to azithromycin, when the drugs were administered alone and together. Size heterogeneity of prolactin secreted from and stored in the rat anterior pituitary gland in vitro. Endogenous adenosine and coronary vasoconstriction in hypoperfused myocardium during exercise. The average size (L) of the synaptic junctions, on the other hand, was increased in alpha-tocopherol deficient rats as compared to normally fed littermates.

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Diffusion of beta-lactam antibiotics into proteoliposomes reconstituted with outer membranes of isogenic imipenem-susceptible and -resistant strains of Enterobacter cloacae. End point measurements as well as kinetic measurements of the formazan production were performed and linear relationships were found between the specific formazan formation and section thickness or incubation time, respectively. The non-dihydropyridine calcium antagonists, verapamil, diltiazem, KB-944, bepridil and MCI-176, are nearly equipotent in producing coronary vasodilatation and a negative dromotropic effect, although all of them are less potent in producing negative inotropy. Analysis and localization of epileptic events using wavelet packets. This injury was accompanied by a significant reduction in the functional sinusoidal density and mitochondrial membrane potential as assessed by Rh123-associated fluorescence in the steatotic liver.

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Here we use coimmunoprecipitation analysis to show that the E5 protein and the activated PDGF receptor exist in a stable complex in transformed mouse C127 cells. Nonviral vector for efficient gene transfer to human ovarian adenocarcinoma cells.

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Classroom behavior and the ability to decode nonverbal cues in boys with severe emotional disturbance. Competitive inhibition of plasma cholesterol esterification by human high-density lipoprotein-subfraction 2.

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New pathways of phagocyte activation: the coupling of receptor-linked phospholipase D and the role of tyrosine kinase in primed neutrophils. Reversible monoubiquitination of PCNA: A novel slant on regulating translesion DNA synthesis. A case reported here of Haloperidol-induced neutropenia demonstrates one of many important drug reactions to which the elderly may be predisposed. Corticosteroids can be safely avoided after POD 1 with the current regimen. Therefore, the optimization of mental health system resources should prompt incentives to better screen, diagnose, and treat patients with a bipolar disorder.

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Visualized CACs in each coronary artery (main, left anterior descending, circumflex, and right) were scored separately as 0 (absent), 1 (mild), 2 (moderate), or 3 (severe), yielding a possible score of 0-12 for each person. Diagnostic value of fine-needle aspiration from parotid gland lesions.

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Neoral C(2) monitoring in pediatric liver transplant recipients. For normal-hearing listeners, the effect of combining maskers was nonlinear, but, additive. Thus, structural information has been obtained that will allow the large scale production of properly folded monomeric PDGF, as well as design of specific PDGF heterodimers. In a single dosage, the combination of phenobarbital and carbamazepine was found to be more effective than its components.

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Assessment of immunity to Pasteurella haemolytica in sheep by in vitro methods. Compared to the effects of nifedipine (10(-7) M), we conclude that Ro 40-5967 (10(-6) M) more effectively prevents the contractions induced by norepinephrine and stimulation of the periarterial nerve and furthermore prevents the amplification of these contractions by endothelin-1. A COMPARISON OF THE SPECIFICITY OF INHIBITION BY PHOSPHONATE ESTERS OF THE FIRST COMPONENT OF COMPLEMENT AND THE ANTIGEN-INDUCED RELEASE OF HISTAMINE FROM GUINEA PIG LUNG.

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Radiology-pathology conference: osteosarcoma in a cartilaginous exostosis of the femur. Mental health services use by elderly adults in a primary care setting. Expression from the promoter of the herpes simplex virus type 2 (HSV-2) large subunit of ribonucleotide reductase (ICP10) is stimulated by co-transfection with DNA that encodes the virion protein Vmw65 previously shown to activate in trans the transcription of all IE genes (Wymer et al., 1989). Conversely, daf-16/FOXO mutants have a defective-arrest phenotype, failing to arrest development and dying rapidly when starved. This extra margin of thermal stability partially resolves the dilemma of how tissues are able to assemble triple-helical procollagen molecules at body temperatures that closely approach the melting temperature of the purified protein.

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Expression and characterization of human mutant (glutamic acid304) medium-chain acyl-coenzyme A dehydrogenase in mammalian cells. In vitro, human breast cancer cell lines T-47D (estrogen-receptor and progesterone-receptor positive) and HCC 1937 (estrogen-receptor and progesterone-receptor negative) were treated with DHEA-S. Older patients are less likely to receive palliative care zoral cream treatment than younger patients.

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HSV-1-infected cultures secreted significant amounts of TNF alpha protein after augmentin pediatric dose intravenous 5 d of culture and reached a maximal level of production at day 7, whereas EBV inhibited TNF alpha production. ON THE BEHAVIOR OF THE URINE ESTROGEN-PREGNANEDIOL RELATION DURING LABOR AFTER INDUCTION WITH ESTRASIDE Ten patients with diffuse toxic goiter, 1-2 nd degree, ten ones with hypothyrosis of medium severity, and a group of healthy controls were examined. For more than a decade, laparoscopic surgery has been adopted as a treatment of colorectal cancer. We review here recent data that have brought into sharper focus a number of important biological properties of the neoplastic cells in childhood primitive neuroectodermal tumors (PNETs) of the central nervous system (CNS).

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