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Multiferon (Ribavirin)

Multiferon is an effective anti-viral drug indicated for treatment of such viral diseases as bronchitis, metastatic melanoma, pneumonia, RSV infection and chronic hepatitis C. Multiferon is in a class of antiviral medications called nucleoside analogues. Multiferon is manufactured by Genentech (member of the Roche group). Multiferon, which is the antiviral active substance of Multiferon, inhibits the multiplication of many types of viruses, including the hepatitis C viruses. Multiferon helps the immune system fight the virus, and makes it harder for the virus to reproduce within the body. Multiferon monotherapy is not effective for the treatment of chronic hepatitis C virus infection (genotypes 1, 2, 3 and 4) and should not be used alone for this indication. Multiferon should be used with such medication as sofosbuvir (Hepcinat) or peginterferon alfa-2a (Pegasys) or peginterferon alpha-2b (PEG-Intron) to treat hepatitis C. Multiferon may also be used to treat severe acute respiratory syndrome (SARS).

Other names for this medication:
Ribavirin, Rebetol, Copegus, Alfater, Beclabuvir, Boceprevir, Daclatasvir, Daklinza, Dasabuvir, Elbasvir, Filibuvir, Hepcinat, Hepcvir, Incivek, Kipferon, Ledifos, Ledipasvir, Miravirsen, Multiferon, Olysio, Ombitasvir, Paritaprevir, Pegasys, Pegetron, Pegintron, Rebetron, Resof, Setrobuvir, Simeprevir, Sofab, Sofovir, Sovaldi, Sylatron, Technivie, Telaprevir, Veldona, Victrelis, Zepatier,

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Multiferon is also sometimes used to treat viral hemorrhagic fevers (viruses that can cause bleeding inside and outside of the body, problems with many organs, and death). In the event of biological warfare, Multiferon may be used to treat viral hemorrhagic fever that has been spread deliberately. Multiferon is also sometimes used to treat severe acute respiratory syndrome (SARS; a virus that may cause breathing problems, pneumonia, and death). Talk to your doctor about the possible risks of using this drug for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

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It has the closest genetic homology, judged from the capacity of its DNA to induce transformation to streptomycin resistance, with H. A closely related group of RNA-dependent RNA polymerases from double-stranded RNA viruses.

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Site-directed mutagenesis of the mecA gene from a methicillin-resistant strain of Staphylococcus aureus. By statistical surrogate analysis, nonlinear phase interaction was found to play an important role in exhibiting universality among multiple cortical regions. In competitive binding assays, bands 1, 2, and 3 but not band 4 were able to compete with live, capacitated, intact sperm for soluble 125I-ZP binding. Furthermore the thrombus formation probably had occurred 6 months earlier. These patients should be considered for permanent cardiac pacing.

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The Cochrane Airways Group Specialised Register was searched, and leaders in the field were contacted. Delta(9)-THC, 11-OH-Delta(9)-THC and Delta(9)-THCCOOH plasma or serum to whole blood concentrations distribution ratios in blood samples taken from living and dead people. In normothermic baboons with arm skin temperature of 34.6 C, the bleeding time was 3.1 minutes. These results seem to confirm that occupational exposure to hydrocarbons is a non-specific factor that may promote a deterioration of renal function. Sperm-induced currents in EGTA-injected eggs had an abrupt onset, quickly reached a maximum, and then slowly declined in amplitude.

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In the head it was been described in cranial base, posterior maxillary surface, maxillary sinus, and different mandibular areas like condyle, ramus, body and symphysis. Assembly, posttranslational processing and intracellular transport of Na,K-ATPase subunits are closely linked processes. The circular arranged sphincteric musculature of bladder neck of female dogs and women were studied histomorphologically.

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The effect of hypoxia on shortening contractions in rat diaphragm muscle. Differences in chemical formulations for adhesive systems may lead to differences in the extent of diffusion-induced water movement and the amount of water within the resin-dentin bonds. However, the pH dependencies of activity for these electron acceptors are significantly different. They can grow to considerable length and cause symptoms such as dysphagia, retrosternal discomfort, vomiting, and even asphyxia.

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After five years of mild, intermittent urticaria, a man had life-threatening idiopathic anaphylactic reactions associated with transient myocardial ischemia, small bowel obstruction, and orthostatic hypotension. The incorporation of thymidine was modestly depressed in the presence of IFN-alpha.

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Effect of pulsatile infusion of gonadotropin-releasing hormone on plasma oestradiol-17 beta concentrations and follicular development during naturally and artificially maintained high levels of plasma progesterone in heifers. The examinations were performed on 37 biological species, with most of them on rats. Inhibitory effects of cardiotonic pills on platelet function in dogs fed a high-fat diet.

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Transfection of nonmelanocytic cells with tyrosinase gene constructs for survival studies. These data, as well as a century of cytogenetic studies, support the argument that meiotic recombination between homologous chromosomes in Drosophila females requires synapsis and SC formation. Comparison of trichloroethylene reductive dehalogenation by microbial communities stimulated on silicon-based organic compounds as slow-release anaerobic substrates. Cholesterol accumulation sequesters Rab9 and disrupts late endosome function in NPC1-deficient cells. The device is comprised of several hundred hollow fiber membranes of approximately 40 cm in length that are woven in a fabric and wrapped around a centrally positioned balloon.

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The bradykinin receptors mediating contraction in smooth muscle of the guinea-pig taenia caeci were compared with the proposed novel B3 receptors of the guinea-pig trachea. The mechanism of formation of empyema of cavum septi pellucidi and cavum Vergae after meningitis in this case is discussed.

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These analyses enabled the identification of seven thrombin-releasable antimicrobial peptides from human platelets: platelet factor 4 (PF-4), RANTES, connective tissue activating peptide 3 (CTAP-3), platelet basic protein, thymosin beta-4 (Tbeta-4), fibrinopeptide B (FP-B), and fibrinopeptide A (FP-A). These data suggest a functional interaction between the CSE2 protein and the yeast centromere. Strategies to augment funding can include political interventions to increase support for the National Center for Health Services Research and Health Care Technology Assessment and to secure designated funds within the National Institutes of Health. Blood flows to the kidneys, placenta and musculoskeletal structures were reduced by 24.7, 38.2 and 35.3 per cent respectively but flow to the brain increased by 30 per cent.

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Elderly patients with diabetes do not appear to be receiving optimal care. Metallation chemistry is considered to be an important area of organometallic chemistry. Unlike the many other experimentally infected animals examined, chimpanzees infected with M. Local coagulation confined to the uterus and adnexa--case description The results, along with current prescriptions obtained from their eye care practitioners, were mailed to the author.

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Open biopsy retrieval of testicular tissue and sperm followed by intracytoplasmic sperm injection. Pharmacokinetics and electrophysiological effects of intravenous ajmaline.

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Antigens from trichinella spiralis that induce a protective response in the mouse. Detecting the limits of bronchial closure methods in an animal model.

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Neither antagonist totally abolished the postprandial peak of the pancreatic protein. The genes of chroideremia and Norrie disease were cloned by positional cloning. We discuss the impact of hyperandrogenemia on the normal ovary as well as its potential role and contribution to anovulation and infertility. Calibrated real-time PCR assay for quantitation of human herpesvirus 8 DNA in biological fluids. Friable asbestos in schools must be found by May 1988, removal plan must start by 1989.

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Auditory brainstem-evoked responses were recorded from 14 children with clinical and radiological evidence of brainstem glioma. Dose-response curves to inhaled NKA (8 to 1,000 micrograms/ml, 0.5 ml/dose) were recorded on 2 randomized days 1 wk apart, and methacholine tests were performed 48 h before and 24 h after the NKA challenge. Bacteria were grown on ferrous ion or elemental sulfur in a Micro-Oxymax respirometer apparatus that allowed measurement of both oxygen consumption and carbon dioxide assimilation. When Winter carp alone were used in an in vivo bioassay, an intracardial injection of up to a dilution of 1/64 hypophyseal equivalent increased plasma concentrations of T4 after 2 and 4 hr.

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Mouse AP47 and nematode UNC-101 proteins are functionally equivalent as assayed in transgenic nematodes. 1H NMR has been used to study the interactions of over 70 clinical and experimental antitumor drugs with DNA. Virginia-type peanut seeds of the extremely dormant variety NC-13 produced low levels of ethylene when imbibed but not germinating.

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These patterns in vitro were in parallel with the dense sympathetic innervation in expansor secundariorum, heart, peripheral blood vessel and abdominal aorta, but little or no sympathetic innervation in lung, skeletal muscle and dorsal aorta in vivo. METHOD OF STABILIZING AUTOPSY SPECIMENS IN BIOMECHANICAL EXPERIMENTS. While clinicians welcomed the information these instruments imparted, their results were rarely incorporated into routine clinical decision making. Epididymal and spermatic cord abnormalities were easily recognized.

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Dose-response relationships must be established to avoid the confusion caused by different investigators using the challenger in different doses. Use of Marlex mesh in the repair of recurrent incisional hernia. Competitive glycosylation experiments with a galactofuranosyl trichloroacetimidate donor were performed with glucosamine acceptors having a free 4-OH group and carrying different protecting groups at N-2, O-3, and O-6.

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Perfluorochemicals in pooled serum samples from United States residents in 2001 and 2002. Segregation analyses of asthma and respiratory allergy: the Humboldt family study.

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STUDIES ON THE EFFECT OF RECOSEN ON THE PULSATION ACTIVITY OF MYOCARDIAL EXPLANTS IN VITRO The important implications for the analysis of fMRI time series for event-related neuroimaging experiments are discussed. Individual prognosis in endogenous affective and schizoaffective psychoses: clinical predictors The purpose of this study is to update the literature and to demonstrate that USAF efforts during the past 19 yr have improved our ability to retain experienced aviators.

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There is little effect of 30-kD protein on the initial rate of elongation from F-actin seeds or on the spontaneous nucleation of actin polymerization. Kindling to the benzodiazepine receptor inverse agonist, FG 7142: evidence for involvement of NMDA, but not non-NMDA, glutamatergic receptors. Light and electron microscopical observations revealed that lipofuscin pigment is present in the spinal ganglia and in the spinal cord, whereas in the sympathetic ganglia both lipofuscin and neuromelanin are present. The presence of a signal peptide is apparently not a conserved feature of all prokaryotic Amt proteins. Hence, pre-operative diagnosis by traditional imaging studies, including computed tomography (CT), has been difficult.

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THE WEIGHT AND CHEMICAL COMPOSITION OF THE HEART OF RATS SUFFERING FROM SIDEROPENIC ANAEMIA IN THE EARLY POSTNATAL PERIOD. The significance of statistical fluctuations and their effects on attenuation are discussed. The patterns of somatic variegation that resulted from transactivation by each fusion were distinct and strikingly different from the pattern triggered by the wild-type Ac constructs. Correlations between the retention times and structures of the bases, the orientations of the secondary hydroxyl groups of the sugar moiety and the anomeric configurations of the nucleosides are also reported. We designed a study to determine the CA diameter (CA(d)) response to exercise (IHG), whether the response is influenced by coronary risk, and compare it with the BAO(cclR) method.

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While infarctions of the right ventricle are being increasingly recognized in the setting of inferior myocardial infarcts, little data on in vivo clot formation in the right ventricle of the heart are available in these patients. Noninvasive diagnosis of renal artery stenosis by ultrasonic duplex scanning.

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However, the strongest relationships are with catchment area and flow, where two straight line relationships are observed. It is also noteworthy that parenteral cigarette smoking may serve as an additional marker of the high-risk patient. We report the first 2 cases of bacterial keratitis resistant to fourth-generation fluoroquinolones after laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK). Our study consisted of 740 consecutive gallbladder cholecyctectomies mostly for cholelithiasis received in a time frame of 3.5 years (for example between January 1997 through to May 2000) by the Department of Histopathology retrieved from the records of the laboratory.

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During the clinical course (approximately 7 months), anti-HBc IgM antibody and HBV-DNA polymerase levels remained high, but the serum alanine aminotransferase (ALT) level was consistently less than 150 K.U. Future research is also needed to understand race/ethnic differentials in prevalence and co-occurrence of these disorders with a particular focus on factors that may give rise to them. We were able to provide statistical evidence that this locus on chromosome 19p13 is most likely not the gene CACNA1A, mutations in which cause FHM.

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The results have unveiled a wealth of stereoelectronic effects that contribute markedly to the stability of collagen, as well as other proteins. Group 4 exhibited nonspecific adhesiveness to the surface of a slide glass. Hepatitis C prevalence and needle/syringe sharing behaviours in recent onset injecting drug users. Despite numerous publications on the ability of immunoscintigraphy to detect recurrent gastrointestinal and ovarian tumors much earlier than other diagnostic methods currently used in the postoperative follow-up, this method has still not received the clinical recognition it deserves.

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To evaluate the clinical outcomes of treating bifurcation lesions with two drug-eluting stent (DES) techniques. Neutron activation analysis of biological samples at the radiochemistry division of IPEN-CNEN/SP.

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The method is primarily suited for the examination of sensory nerves. Four human cadavers and the Hybrid III dummy were used as occupants in 32 km/h and 48 km/h tests with a simulated mid-size vehicle. The acylureidopenicillins azlocillin and mezlocillin cover a broad spectrum of bacteria, including gramnegative and grampositive species as well as anaerobes. Influenza A viruses: epidemiologic study in fatteners in Spain (1987-89).

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Epidermal growth factor (EGF) and TGFalpha are well known for their activities in the ovary. This use of a two-level scoring makes PAS-Dock computationally efficient, and well suited for virtual screening.

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The purpose of this study was to investigate, by radioluminographic and microscopic techniques, the regional effects of the two complementary therapies. Evidence of genetic heterogeneity among the nondystrophic myotonias. INTER- AND INTRAGENERATIONAL DIFFERENCES IN MATERNAL ATTITUDES TOWARDS CHILD REARING.

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The analysis of the data showed that morphological and functional characteristics of the neurons in question corresponded completely to previously identified multifunctional interneuron V21. Outcome in consecutive emergency department attenders following a road traffic accident. Since this study was performed under moderate hypoxia, reduction in oxygen pressure seems not to be a crucial factor for venous thrombosis at long-haul flights. The aforementioned non-invasive method and attachment were used. A case is presented of an adolescent who developed an unusual swelling on his back after persistent vigorous involvement in break dancing.

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A one year old Hereford female calf showed slow growth, brachygnathia superior, hyper-salivation. Genetic studies suggest that angiopoietin/Tie2 signaling may play a role in the recruitment of pericytes or smooth muscle cells (SMCs) during vascular maturation. The ability of several known anti-HIV substances to inhibit feline immunodeficiency virus (FIV) was tested.

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Numerous finger-like processes were observed on the cell bodies of the studded neurons in close relationship with the varicose axons. Sleep staging and respiratory variables were monitored during all studies.

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The reagent was synthesized in a heavy form (13C phenyl ring), showing no chromatographic shift and an optimal isotopic separation with a 6 Da mass shift. Frequencies below 10 kHz passed almost unaffected, while attenuation in excess of spherical attenuation increased at higher frequencies. Specific binding sites for hCG were present in Stage 1 and 2 follicles (2 layers of granulosa cells) but thereafter their distribution was erratic and they were not consistently detectable until Stage 5, when thecal cells first appeared. Reinnervation of hind limb muscles after ventral root avulsion and implantation in the lumbar spinal cord of the adult rat. Secondary ureteroneocystostomy is the procedure most commonly used for repair of ureteral stenosis or necrosis in renal transplant patients.

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In 196 human embryos, prefetuses, fetuses and newborns, by means of a complex of morphological methods, development of the jugular lymphatic sacs and the process of settling of the thoracic duct cervical part topography have been studied. One week later, the animals were perfusion fixed, and the superior cervical ganglia (SCG) were removed, embedded in paraffin, and serially sectioned at 10 microns. botulinum type C in reference laboratories was based on 16S rDNA sequence data and specific neutralisation of cytopathic effects in tissue culture. The Ac locus was shown to segregate independently of the S incompatibility locus.

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In contrast, Rb and Zn levels were increased when lead was administered for the longer period at both dose levels. Immunostaining showed intense expression of EMMPRIN, MMP-2, MT1-MMP and MT2-MMP in dermal structures of venous leg ulcers, whereas only EMMPRIN and MMP-2 showed elevated expression in perivascular regions. Alterations in absorption, metabolism, and excretion may conserve calcium when requirements increase.

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Most of the TK6 clones surviving exposure to 56Fe ions showed unstable cytogenetic abnormalities, while the phenotype of the WTK1 clones was more diverse. Hormone levels in yolk decline throughout development in the red-eared slider turtle (Trachemys scripta elegans). Invasive and noninvasive assessment of coronary artery bypass graft patency This study compared paired mucosal and dermal fibroblasts in terms of collagen gel contraction, alpha-smooth muscle actin expression (alpha-SMA), and production of the epithelial growth factors: keratinocyte growth factor (KGF) and hepatocyte growth factor/scatter factor (HGF).

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Rapid diagnosis with the use of this test is based on different time of the appearance of the lysis areas: in bacterial meningitides the CSF lysozyme activity is detectable within 15-120 min, whereas in viral meningitides it manifests 40-50 min later or does not manifest at all. Hypotonic treatment evokes biphasic ATP release across the basolateral membrane of cultured renal epithelia (A6).

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Histopathological findings indicated degeneration and necrosis in epithelial cells of the proximal convolute tubuli and thickening of basement membrane. Since a lot of patients turn to them for a first consultation, they should be familiar with the main diagnostic aspects of these disorders. Hepcidin concentrations in urine negatively correlate with the severity of HH.

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The organization of the dispensary observation of patients with respiratory organ sarcoidosis We then discuss the implications of these results for isochore evolution in vertebrates. DNA supercoiling plays an indispensable role in an early step of bacteriophage Mu transposition. The development of posttransplantation diabetes mellitus has a major impact on the quality of life and long-term outcome.

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Assessment of the rhythm of lymphocyte stimulation and suppression as a criterion of prognosis of the effects of immunomodulatory drugs APPLICATION OF QUANTITATIVE SPECTRAL ANALYSES TO BINARY MIXTURES OF THE COMMON CAROTENOIDS. The results of this study support the possibility that cocaine and CMV could enhance HIV-1 replication and, thus, aggravate HIV-1-related disease. A comparison by two-dimensional gel electrophoresis of the tRNA populations extracted from chloroplasts and from chloroplast polysomes shows that all chloroplast tRNAs are involved in protein biosynthesis. Changes in sun-related attitudes and behaviours, and reduced sunburn prevalence in a population at high risk of melanoma.

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This resetting between trials appears to reflect the operation of an active working memory process rather than a passive temporal decay in a neuronal response. The impact of diabetes mellitus at the time of heart transplantation on long-term survival. This approach requires the availability of cell lines and CTLs against cancers. However, stem cells differentiate, and the telomere length differs among chromosomes within a single cell, among cell types, and among age-matched individuals.

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Whether thymus size at birth is related to total expal syrup brands serum IgE levels still remains to be elucidated. The IUS-12 also demonstrated a stable two-factor structure, representing both anxious and avoidance components of intolerance of uncertainty. Depressive symptoms and the dexamethasone suppression test in parkinsonian patients.

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As the requirement for prevention and treatment of the peritoneal surface component of que es lertus forte lighting gastrointestinal and gynecologic oncology expands, new investigations into the approval process in the United States will be necessary. Without additional training, retina specialists may be the most reliable personnel to interpret single-field digital fundus images for diabetic retinopathy screening.

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Acute cholestatic hepatitis caused by Teucrium polium (golden germander) with transient appearance of antimitochondrial antibody. Human parvovirus-induced transient anemia and leukopenia cephalexin liquid ingredients after delivery

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Blood lead levels halfwaardetijd diclofenac gel in relation to paint and dust lead levels: the lead-safe cambridge program. Activity of acyl-CoA:cholesterol acyltransferase was within the normal range in cell-free extracts of both LDL-depleted and LDL-supplemented cultures of Niemann-Pick C and D fibroblasts.

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Video display terminal use and reported health symptoms among Massachusetts clerical workers. We followed a cohort of 7,666 individuals enrolled continuously for five years in a prepaid group practice in Columbia, Maryland. Swiss adjuvant trial (OSAKO 06/74) with chlorambucil, liquid tight flexible conduit carlon methotrexate, and 5-fluorouracil plus BCG in node-negative breast cancer patients: nine-year results. Clinicopathologic reports, case reports, and small case series: progressive growth of benign adenoma of the pigment epithelium of the ciliary body. Following the tentative diagnosis of dermal tuberculosis, histological, microbiological and X-ray examinations were performed.

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In the damp-wood termite Hodotermopsis sjostedti, we induced primazole syrup source differentiation into the soldier caste by using juvenile hormone analogue treatment. Inactivated hepatitis A vaccine: active and passive immunoprophylaxis in chimpanzees.

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In situ hybridization analysis of osteoactivin in normal bone revealed that it is primarily expressed in osteoblasts actively engaged in bone matrix production and mineralization. The macrolide antibiotics clarithromycin effect of absorbable self-reinforced polyglycolide membrane on metaphyseal bone. Experience with U-shaped gluteal thigh flap for reconstruction of radionecrosis in the sacral region. EFFECT OF EXPERIMENTAL PERFUSION UPON THE BIOLOGIC AND PATHOLOGIC BEHAVIOR OF TUMOR. Effects of pericardiotomy on the diastolic function of the inflow chamber of the right ventricle

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Maximal pulmonary ventilation and the diclofenac sandoz 50 mg posologie du forced expiratory rate under hyperbarism Mechanism of action of remantadine hydrochloride on Sindbis virus reproduction: inhibition of virus penetration into the cell